Bis-(2-hydroxydecyl)-sulfoxid | 26073-94-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 亚砜
• 英文名称: Bis-(2-hydroxydecyl)-sulfoxid
• 英文别名: 1-(2-Hydroxydecylsulfinyl)decan-2-ol
• CAS: 26073-94-9
• 化学式: C₂₀H₄₂O₃S
• 分子量: 362.618
• InChiKey: GRNIEUCNVBUFEX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  24
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  76.7
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Advanced drug development and manufacturing
  申请人：Los Alamos National Security, LLC

  公开号：EP2511844A2

  公开（公告）日：2012-10-17

  There is described an apparatus for measuring protein characteristics comprising an X-ray fluorescence (XRF) spectrometer comprising a source of polychromatic X-rays, an X-ray detector, a protein, a molecule that has been exposed to and at least weakly binds to the protein, a plurality of X-ray fluorescence signal data obtained by irradiating chemical elements in the protein and molecule with the polychromatic X-rays and a security system for maintaining records for the data from the plurality of X-ray fluorescence signal measurements. There is also described an x-ray microscope for measuring a sample.

  描述了一种测量蛋白质特性的仪器，该仪器包括一个 X 射线荧光 (XRF) 光谱仪，其中包括一个多色 X 射线源、一个 X 射线探测器、一个蛋白质、一个已暴露于该蛋白质并至少与该蛋白质弱结合的分子、通过用多色 X 射线照射蛋白质和分子中的化学元素而获得的多个 X 射线荧光信号数据，以及一个用于维护多个 X 射线荧光信号测量数据记录的安全系统。此外，还介绍了一种用于测量样品的 X 射线显微镜。
• Products useful for the treatment of malignant neoplasms of the human nervous system
  申请人：Institut Pasteur

  公开号：EP2581384A1

  公开（公告）日：2013-04-17

  The application provides products, which may trigger pro-apoptotic or pro-death effects on neoplastic cells and/or tissues of the human nervous system, more particularly on neoplastic cells and/or tissues of the human CNS. The products of the application can be used as anti-proliferative or tumoricid agents in the treatment and/or palliation and/or prevention of neoplasms of the human nervous system, more particularly of glioblastoma or brain stem glioma. Therefore, the application also relates to compositions, such as pharmaceutical compositions or drugs, which comprise at least one of said products, as well as to the biotechnological and medical applications of said products and compositions.

  本申请提供的产品可对人类神经系统的肿瘤细胞和/或组织，尤其是人类中枢神经系统的肿瘤细胞和/或组织产生促凋亡或促死亡效应。本申请的产品可用作抗增殖剂或抗肿瘤剂，用于治疗和/或缓解和/或预防人类神经系统肿瘤，尤其是胶质母细胞瘤或脑干胶质瘤。因此，本申请还涉及包含至少一种上述产品的组合物，如药物组合物或药物，以及上述产品和组合物的生物技术和医学应用。
• Carrier based on granules produced from pyrogenically prepared silicon dioxides
  申请人：Neugebauer Peter

  公开号：US20060229210A1

  公开（公告）日：2006-10-12

  Carrier based on granules produced from pyrogenically prepared silicon dioxides. The use of granules produced from pyrogenically prepared silicon dioxides as carriers for substances including foodstuffs additives, such as dyestuffs, antioxidants, preservatives, emulsifiers, gelling agents, thickeners and binders, stabilizers, alkalis, acids, salts, antilumping agents, flavour intensifiers, sweeteners, aromas; feedstuff additives; chemical intermediates and plant protection agents.

  基于热原制备的二氧化硅颗粒的载体。利用热致制备的二氧化硅生产的颗粒作为载体，用于载入各种物质，包括食品添加剂，如染料、抗氧化剂、防腐剂、乳化剂、胶凝剂、增稠剂和粘合剂、稳定剂、碱、酸、盐、防结块剂、增味剂、甜味剂、芳香剂；饲料添加剂；化学中间体和植物保护剂。
• ADVANCED DRUG DEVELOPMENT AND MANUFACTURING
  申请人：Los Alamos National Security, LLC

  公开号：EP2084519A2

  公开（公告）日：2009-08-05
• X-RAY FLUORESCENCE ANALYSIS METHOD
  申请人：Los Alamos National Security, LLC

  公开号：EP2084519B1

  公开（公告）日：2012-08-01