(N,N-diisopropylaminoethyl)trimethylstannane | 828913-26-4

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机过渡后金属化合物
• 英文名称: (N,N-diisopropylaminoethyl)trimethylstannane
• 英文别名: N-propan-2-yl-N-(trimethylstannylmethyl)propan-2-amine
• CAS: 828913-26-4
• 化学式: C₁₀H₂₅NSn
• 分子量: 278.025
• InChiKey: HTPNIXVSBQEIKW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.98
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  trimethylstannylmethyl iodide 、 二异丙胺 在 K₂CO₃ 作用下， 以 乙腈 为溶剂， 以65%的产率得到(N,N-diisopropylaminoethyl)trimethylstannane
  参考文献：
  名称：

  N,N-Diisopropylaminomethyllithium:  Synthesis, Oxidative Degradation, and Organoaluminum and -gallium Derivatives

  摘要：

  N,N-Diisopropylaminomethyllithium (1) was prepared by transmetalation from (Me3SnCH2NPr2)-Pr-i and n-BuLi. It was characterized by NMR spectroscopy (H-1, C-13, Li-7). Compound 1 crystallizes as a hexamer ((LiCH2NPr2)-Pr-i)(6) and allowed the determination of the first solvent-free structure of an alpha-lithiated amine. It contains a Li-6 core (distorted octahedron) 6-fold capped by (CH2NPr2)-Pr-i units. 1 is very sensitive to air-oxidation. A partially [(LiCH2NiPr2)(4)-(LiOCH2NiPr2)(2) (2)] and a completely oxidized [((LiOCH2NPr2)-Pr-i)(6) (3)] cluster compound could be isolated. 2 and 3 were characterized by multinuclear NMR spectroscopy and by single-crystal X-ray diffraction. The results show that the hexameric structure is retained upon partial or complete oxidation. 1 was used as aminomethylating agent and reacted with Me2AlCl and Me2GaCl to give the aminomethylaluminum and -gallium compounds ((Me2MCH2NPr2)-Pr-i)(2) (M = Al, Ga), which are dimers containing six-membered rings. They were characterized by elemental analyses, NMR spectroscopy, and crystal structure determinations. They are present as dimers containing six-membered M2C2N2 rings in solution and in the solid state.

  DOI：

  10.1021/om049631i