(Z)-3-(bromomethylene)-7-fluoro-6-methylisothiochroman-4-one | 1251530-95-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 硫铬烷
• 英文名称: (Z)-3-(bromomethylene)-7-fluoro-6-methylisothiochroman-4-one
• 英文别名: (3Z)-3-(bromomethylidene)-7-fluoro-6-methyl-1H-isothiochromen-4-one
• CAS: 1251530-95-6
• 化学式: C₁₁H₈BrFOS
• 分子量: 287.152
• InChiKey: IYHRXIMKTUQSKU-WMZJFQQLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• PREPARATION AND APPLICATION OF NOVEL ANTIBACTERIAL AND ANTICANCER COMPOUNDS AND THEIR DERIVATIVES
  申请人：Yang Gengliang

  公开号：US20120035206A1

  公开（公告）日：2012-02-09

  Novel antibiotic and anticancer compounds of formula I, II, III, IV, derivatives, ostereoisomer, racemic and noracemic mixture of ostereoisomer, or the pharmaceutically acceptable salts or solvates of these compounds are disclosed. The preparation, pharmaceutical composition and biological activity of these compounds are disclosed.

  本发明揭示了化学式I、II、III、IV、衍生物、对映异构体、外消旋和非外消旋对映异构体混合物，或这些化合物的药学上可接受的盐或溶剂化物的新型抗生素和抗癌化合物。本发明还揭示了这些化合物的制备、制药组合物和生物活性。
• PREPARATION AND APPLICATION OF THE NEW ANTIBACTERIAL AND ANTICANCER COMPOUNDS AND THEIR DERIVATIVES
  申请人：YANG Gengliang

  公开号：US20140296285A1

  公开（公告）日：2014-10-02

  A method of inhibiting microorganism growth comprising administering an effective amount of a composition including a compound selected from the group consisting of to the microorganism.

  一种抑制微生物生长的方法，包括向微生物施加包含以下化合物中的一种所选的组合物的有效量。
• PREPARATION AND USE OF NOVEL ANTIBIOTIC, ANTICANCER COMPOUNDS AND DERIVATIVES THEREOF
  申请人：Yang, Gengliang

  公开号：EP2423213A1

  公开（公告）日：2012-02-29

  Novel antibiotic and anticancer compounds compounds of formula I, II, III, IV, derivatives , stereoisomer , racemic and noracemic mixture of stereoisomer , or the pharmaceutically acceptable salts or solvates of these compounds are disclosed. The preparation, pharmaceutical composition and biological activity of these compounds are disclosed.

  本研究公开了新型抗生素和抗癌化合物式 I、II、III、IV、衍生物、立体异构体、立体异构体的外消旋和去消旋混合物或这些化合物的药学上可接受的盐或溶液。公开了这些化合物的制备方法、药物组成和生物活性。