diisopropylamine-cis-2,6-dimethyl-N-piperidylmethylidene | 873686-40-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: diisopropylamine-cis-2,6-dimethyl-N-piperidylmethylidene
• 英文别名: N,N-diisopropylamino-cis-2,6-dimethylpiperidinocarbene
• CAS: 873686-40-9
• 化学式: C₁₄H₂₈N₂
• 分子量: 224.39
• InChiKey: RHSLQRDEEKJAKM-OKILXGFUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.36
• 重原子数：
  16.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  6.48
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  diisopropylamine-cis-2,6-dimethyl-N-piperidylmethylidene 、 trans-di(μ-acetato)bis[o-(di-o-tolylphosphino)benzyl]dipalladium(II) 以 甲苯 为溶剂， 以73%的产率得到acetato [diisopropylamine-cis-2,6-dimethyl-N-piperidylmethylidene][o-(di-o-tolylphosphino)benzyl]palladium(II)
  参考文献：
  名称：

  Novel acyclic carbene-substituted phospha-palladacycles

  摘要：

  Here, we report the synthesis of the first phospha-palladacycle substituted with an acyclic carbene. The reaction of bis(dialkyl)aminocarbenes with the very stable phospha-palladacycles leads to metastable eta(1)-carbene complexes, which can be converted by intramolecular reduction to zero valent palladium complexes. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2005.07.055
• 作为产物：
  描述：

  diisopropyl-(cis-2,6-dimethylpiperidine-1-ylmethylidene)ammonium dichlorophosphate 以63%的产率得到diisopropylamine-cis-2,6-dimethyl-N-piperidylmethylidene
  参考文献：
  名称：

  Novel acyclic carbene-substituted phospha-palladacycles

  摘要：

  Here, we report the synthesis of the first phospha-palladacycle substituted with an acyclic carbene. The reaction of bis(dialkyl)aminocarbenes with the very stable phospha-palladacycles leads to metastable eta(1)-carbene complexes, which can be converted by intramolecular reduction to zero valent palladium complexes. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2005.07.055

文献信息

• Unexpected thermal decomposition of the “Alder carbene” (iPr2N)2C
  作者：Tim Schulz、Michael Leibold、Christian Färber、Martin Maurer、Timo Porsch、Max C. Holthausen、Ulrich Siemeling

  DOI：10.1039/c2cc34208a

  日期：——

  The "Alder carbene" (iPr(2)N)(2)C undergoes a beta-fragmentation in solution already at room temperature, affording propene and N,N,N'-triisopropylformamidine. This stands in sharp contrast to the indefinite stability previously claimed for this iconic compound.

  所述 “阿尔德卡宾”（的iPr（2）N）（2）C经历溶液β-碎片已经在室温下，得到丙烯和N，N，N'- triisopropylformamidine。此形成鲜明的对比，以先前声称对这个标志性化合物无限期稳定。