N-ditert-butylphosphanylpropan-2-amine | 64067-68-1

• 分子结构分类: 有机化合物 - 有机磷化合物
• 英文名称: N-ditert-butylphosphanylpropan-2-amine
• CAS: 64067-68-1
• 化学式: C₁₁H₂₆NP
• 分子量: 203.308
• InChiKey: IIUMKZCHXVFYOJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-ditert-butylphosphanylpropan-2-amine 在 selenium 作用下， 以 乙醚 、 正己烷 、 甲苯 为溶剂， 反应 2.0h， 生成 N-ditert-butylphosphinoselenoylpropan-2-amine
  参考文献：
  名称：

  Synthesis of selenophosphinic and tellurophosphinic amides and amidato complexes. Crystal structures of Bu^t₂P(Te)NH(C₆H₁₁), [Ti(η-C₅H₅)Cl₂{Bu^t₂P(Se)NPrⁱ}] and [TiCl₂{Bu^t₂P(Se)N(C₆H₁₁)}₂]·C₇H₈

  摘要：

  The reaction of Bu(2)(t)PNHR' with selenium or tellurium affords the chalcogenophosphinic amides Bu(2)(t)P(E)NHR' (E = Se or Te; R' = Pr-i or cyclo-C6H11). The compounds [Bu(2)(t)P(E)NHCH2](2) were prepared similarly. The crystal structure of Bu(2)(t)P(Te)NH(C6H11) was determined; it shows a short P-Te bond of 2.371(1) Angstrom and a rather long P-N bond of 1.781(4) Angstrom. The lithium salts Li[Bu(2)(t)P(Se)NR'] react with [TiCl3(cp)] (cp = eta-C5H5) to give [TiCl2(cp){Bu(2)(t)P(Se)NR'}]. The reaction of Li[Bu(2)(t)P(Se)NPri] with [TiCl4(thf)(2)] (thf = tetrahydrofuran) affords [TiCl3{Bu(2)(t)P(Se)NPri)]. while a similar reaction with Li[Bu(2)(t)P(Se)N(C6H11)] leads to the isolation of [TiCl2{Bu(2)(t)P(Se)N(C6H11}(2)]. The structures of [TiCl2(cp){Bu(2)(t)P(Se)NPri}] and [TiCl2{Bu(2)(t)P(Se)N(C6H11)}(2)]. C7H8 have been determined by X-ray crystallography. The selenophosphinic amidato ligands are bidentate in ail cases. The former complex adopts a distorted square-pyramidal geometry with apical cp, while the latter is octahedral with cis-CI ligands and trans stereochemistry for the nitrogen donors.

  DOI：

  10.1039/dt9950001887
• 作为产物：
  描述：

  二叔丁基氯化膦 、 异丙胺 在 正丁基锂 作用下， 以 乙醚 、 正己烷 、 甲苯 为溶剂， 生成 N-ditert-butylphosphanylpropan-2-amine
  参考文献：
  名称：

  Synthesis of selenophosphinic and tellurophosphinic amides and amidato complexes. Crystal structures of Bu^t₂P(Te)NH(C₆H₁₁), [Ti(η-C₅H₅)Cl₂{Bu^t₂P(Se)NPrⁱ}] and [TiCl₂{Bu^t₂P(Se)N(C₆H₁₁)}₂]·C₇H₈

  摘要：

  The reaction of Bu(2)(t)PNHR' with selenium or tellurium affords the chalcogenophosphinic amides Bu(2)(t)P(E)NHR' (E = Se or Te; R' = Pr-i or cyclo-C6H11). The compounds [Bu(2)(t)P(E)NHCH2](2) were prepared similarly. The crystal structure of Bu(2)(t)P(Te)NH(C6H11) was determined; it shows a short P-Te bond of 2.371(1) Angstrom and a rather long P-N bond of 1.781(4) Angstrom. The lithium salts Li[Bu(2)(t)P(Se)NR'] react with [TiCl3(cp)] (cp = eta-C5H5) to give [TiCl2(cp){Bu(2)(t)P(Se)NR'}]. The reaction of Li[Bu(2)(t)P(Se)NPri] with [TiCl4(thf)(2)] (thf = tetrahydrofuran) affords [TiCl3{Bu(2)(t)P(Se)NPri)]. while a similar reaction with Li[Bu(2)(t)P(Se)N(C6H11)] leads to the isolation of [TiCl2{Bu(2)(t)P(Se)N(C6H11}(2)]. The structures of [TiCl2(cp){Bu(2)(t)P(Se)NPri}] and [TiCl2{Bu(2)(t)P(Se)N(C6H11)}(2)]. C7H8 have been determined by X-ray crystallography. The selenophosphinic amidato ligands are bidentate in ail cases. The former complex adopts a distorted square-pyramidal geometry with apical cp, while the latter is octahedral with cis-CI ligands and trans stereochemistry for the nitrogen donors.

  DOI：

  10.1039/dt9950001887

文献信息

• A Convenient Approach to <i>N</i> ‐(Di‐ <i>tert</i> ‐butylphosphanyl)‐ and <i>N</i> ‐(Di‐ <i>tert</i> ‐butylphosphoroselenoyl)formamidinium Salts: Carbene Precursors
  作者：Anatoliy Marchenko、Georgyi Koidan、Anastasiya Hurieva、Aleksandr Savateev、Alexander B. Rozhenko、Jean‐Marc Sotiropoulos、Svitlana V. Shishkina、Oleg V. Shishkin、Aleksandr Kostyuk

  DOI：10.1002/ejic.201301365

  日期：2014.3

  N-(di-tert-butylphosphoroselenoyl)formamidinium salts. The phosphinoselenoic amides with bulky substituents (adamantyl, tBu) underwent cleavage of the N–alkyl bond to afford phosfams. Various key intermediates such as 3 and 22b were isolated and characterized. A convenient method for the synthesis of carbene precursor PIII and PV N-substituted formamidinium salts was developed.

  研究了(二叔丁基膦酰基)胺和P,P-二叔丁基膦硒酸酰胺与Alder's二聚体的反应。对于二叔丁基膦酰胺，反应通过 Alder 二聚体在磷原子上的初级亲电攻击进行，以提供双阳离子盐 3。3 的去质子化导致 N-膦酰甲脒5（“磷酰胺”）。烷基（二叔丁基膦酰基）胺与阿尔德氏二聚体以 2:1 的摩尔比反应，得到 N-膦酰基甲脒盐；第二当量的（烷基氨基）膦作为碱。(芳氨基)膦与Alder的二聚体反应得到苯氮杂磷衍生物。为了指导阿尔德二聚体在氮原子上的亲电攻击，使用了膦硒酸酰胺。他们与阿尔德反应 硒原子上的二聚体，然后是硒-磷位移，得到 N-（二叔丁基磷硒酰）甲脒盐。具有庞大取代基（金刚烷基，tBu）的膦亚硒酰胺经历了 N-烷基键的断裂，得到了磷酰胺。分离和表征了各种关键中间体，例如 3 和 22b。开发了一种合成卡宾前体 PIII 和 PV N-取代甲脒盐的简便方法。
• Kuchen, W.; Langsch, D.; Peters, W., Phosphorus, Sulfur and Silicon and the Related Elements, 1990, vol. 54, # 1/4, p. 55 - 61
  作者：Kuchen, W.、Langsch, D.、Peters, W.

  DOI：——

  日期：——
• Gurov, M. V.; Veits, Yu. A.; Torocheshnikov, V. N., Russian Journal of General Chemistry, 1994, vol. 64, # 3.1, p. 365 - 370
  作者：Gurov, M. V.、Veits, Yu. A.、Torocheshnikov, V. N.、Tsvetkov, D. E.、Foss, V. L.、Ustynyuk, Yu. A.

  DOI：——

  日期：——
• KUCHEN, W.;LANGSCH, D.;PETERS, W., PHOSPH., SULFUR AND SILICON AND RELAT. ELEM., 54,(1990) N-4, C. 55-61
  作者：KUCHEN, W.、LANGSCH, D.、PETERS, W.

  DOI：——

  日期：——