4-(phenyldiazenyl)phenyl 2-(((ethylthio)carbonothioyl)thio)-2-methylpropanoate | 1246920-90-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: 4-(phenyldiazenyl)phenyl 2-(((ethylthio)carbonothioyl)thio)-2-methylpropanoate
• CAS: 1246920-90-0
• 化学式: C₁₉H₂₀N₂O₂S₃
• 分子量: 404.578
• InChiKey: AWHUUUPLVJRICF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.56
• 重原子数：
  26.0
• 可旋转键数：
  6.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  51.02
• 氢给体数：
  0.0
• 氢受体数：
  7.0

反应信息

• 作为产物：
  描述：

  2-[[(乙硫基)硫代甲酰]硫代]-2-甲基-丙酸 、 4-N-苯基苯酰胺 在 4-二甲氨基吡啶 、 N,N'-二环己基碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 反应 25.0h， 以84%的产率得到4-(phenyldiazenyl)phenyl 2-(((ethylthio)carbonothioyl)thio)-2-methylpropanoate
  参考文献：
  名称：

  Dual Stimuli-Responsive Supramolecular Hydrogel Based on Hybrid Inclusion Complex (HIC)

  摘要：

  A novel dual-responsive supramolecular hydrogel composed of an azobenzene (AZO) end-functionalized block copolymer PDMA-b-PNIPAM (AZO-(PDMA-b-PNIPAM)) and beta-cyclodextrin-modified CdS quantum clot (beta-CD@QD) has been demonstrated. Based on the host-guest inclusion complexation of AZO of the block copolymers and Cl) cavities on beta-CD@QD, they form a hybrid inclusion complex (HIC). The HIC contains a QD as the core and the block copolymer as the shell with the PNIPAM block as the outer layer. Dynamic light scattering (DLS) and UV-vis spectroscopy investigation proved the HIC structure in diluted solution. Hydrogel formed easily upon heating the aqueous solution of HIC at a concentration as low as 7 wt %; as a result of PNIPAM, aggregation occurred above the LCST. The inclusion complex and the domains of the collapsed PNIPAM chains serve as two distinct cross-links and render the hydrogel excellent dual sensitivity to competitive hosts/guests substitution and to temperature variation. Furthermore, rheology results quantitatively exhibit the hydrogel formation mechanism and the sot-to-gel reversibility following the two external stimuli.

  DOI：

  10.1021/ma101437k