2-amino-1-trimethylsiloxybutane | 82935-67-9

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 2-amino-1-trimethylsiloxybutane
• 英文别名: 1-trimethylsilyloxybutan-2-amine
• CAS: 82935-67-9
• 化学式: C₇H₁₉NOSi
• 分子量: 161.319
• InChiKey: OTOBKGJKWPZFDI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.58
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-(2-氧代环戊基)丙腈 、 2-amino-1-trimethylsiloxybutane 在 二丁基二氯化锡 作用下， 以 甲苯 为溶剂， 以71%的产率得到3-[2-(1-trimethylsilyloxybutan-2-ylimino)cyclopentyl]propanenitrile
  参考文献：
  名称：

  Stetin, C.; Jeso, B. de; Pommier, J.C., Synthetic Communications, 1982, vol. 12, # 7, p. 495 - 500

  摘要：

  DOI：
• 作为产物：
  描述：

  2-氨基-1-丁醇 、 六甲基二硅氮烷 在 tributyltin grafted on 3-aminopropyl functionalized γ-Fe2O3 nanoparticles 作用下， 以 乙腈 为溶剂， 反应 0.17h， 以85%的产率得到2-amino-1-trimethylsiloxybutane
  参考文献：
  名称：

  Tributyltin grafted onto the surface of 3-aminopropyl functionalized γ-Fe₂O₃nanoparticles: a magnetically-recoverable catalyst for trimethylsilylation of alcohols and phenols

  摘要：

  在功能化磁性纳米粒子表面固定均质三丁基氯化锡催化剂，提供了一种新的稳定、高效且可通过磁力回收的催化剂，用于在温和反应条件下进行醇和酚的六甲基二硅氮烷的甲基化反应。该催化剂表现出良好的稳定性，至少可重复使用10次。催化剂通过光谱、磁性和热技术（FT-IR、SEM、TEM、XRD、ICP、VSM和TGA）进行了表征。

  DOI：

  10.1039/c4ra04911j

文献信息

• Synthesis and characterization of chiral and thermo responsive amphiphilic conetworks
  作者：Jan Tobis、Yi Thomann、Joerg C. Tiller

  DOI：10.1016/j.polymer.2009.10.055

  日期：2010.1

  Amphiphilic polymer conetworks (APCN) combine the properties of different polymers on the nanoscale affording advanced materials with unique properties. Here, we present the first APCN with a chiral hydrophilic phase. The conetworks were prepared by copolymerizing the tailored chiral monomer (R)-N-(1-hydroxybutan-2-yl)acrylamide (R-HBA) with two different crosslinkers that consist of bitelechelic methacrylate-terminated poly(dimethylsiloxane) (PDMS) of a molecular weight of 1100g/mol and 5620 g/mol, respectively. The resulting polymer conetworks P-R-HBA-l-PDMS exhibited both two different T-g values, indicating nanophase separation. However, the conetwork with PDMS1.1 did not show nanophases in the AFM and did not swell the phases separately in orthogonal solvents. On the other hand the materials with PDMS5.6 acted like a typical APCN. The APCN P-R-HBA-l-PDMS5.6 was found to be temperature sensitive in water, decreasing its degree of swelling linearly with increasing temperature. Additionally, the conetwork is increasing its degree of swelling in n-heptane in the region of the T-g of the P-R-HBA phase. The impact of the chiral polymer on the release of cinchona alkaloids was examined. For example, (-)-cinchonine diffuses four times faster off the P-R-HBA-l-PDMS networks than off the P-S-HBA-l-PDMS conetworks. (C) 2009 Elsevier Ltd. All rights reserved.
• ——
  作者：A. S. Medvedeva、M. V. Andreev、L. P. Safronova、G. I. Sarapulova、D. V. Pavlov、A. V. Afonin

  DOI：10.1023/a:1015334204435

  日期：——

  A number of previously unknown N-(2-hydroxyethyl)trimethylsilylpropynamides were synthesized by reactions of 2-aminoethyl trimethytsilyl ethers with trimethylsilylpropynoyl chloride. 2-Hydroxyethylamine reacts with trimethylsilylpropynoyl chloride at both nitrogen and oxygen atoms to afford 2-(3-trimethylsilyl-propynoylamino)ethyl trimethylsilylpropynoate.