紫葳鹼 | 6878-83-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 紫葳鹼
• 英文名称: tecomine
• 英文别名: tecomanine；(7aS)-2,4t,7c-trimethyl-(7ar)-1,2,3,4,7,7a-hexahydro-[2]pyrindin-6-one；(7aS)-2,4t,7c-Trimethyl-(7ar)-1,2,3,4,7,7a-hexahydro-[2]pyrindin-6-on；(4R,7S,7aS)-2,4,7-trimethyl-3,4,7,7a-tetrahydro-1H-cyclopenta[c]pyridin-6-one
• CAS: 6878-83-7
• 化学式: C₁₁H₁₇NO
• 分子量: 179.262
• InChiKey: QGCAKXUASFKRJA-NRPADANISA-N

物化性质

• 比旋光度：
  D24 -175° (c = 1.17 in CHCl3)
• 沸点：
  bp0.1 125°
• 密度：
  1.04±0.1 g/cm3(Predicted)
• 熔点：
  <25 °C

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  borane;(4R)-2,4,7-trimethyl-3,4,5,7-tetrahydro-1H-cyclopenta[c]pyridin-6-one 、 乙醇 生成 紫葳鹼
  参考文献：
  名称：

  BRAYER, J. -L.;ALAZARD, J. -P.;THAL, C., TETRAHEDRON LETT., 29,(1988) N 6, 643-646

  摘要：

  DOI：

文献信息

• A Zirconium-Mediated Synthesis of (±)-Tecomanine
  作者：Mark I. Kemp

  DOI：10.1055/s-1998-5924

  日期：1998.3
• Alcaloïdes monoterpéniques: Synthèse stéréospécifique de la Δ-7(7a) 4a-βH isotécomanine
  作者：J.-L. Brayer、J.-P. Alazard、C. Thal

  DOI：10.1016/s0040-4039(00)80171-9

  日期：——
• BRAYER, J. -L.;ALAZARD, J. -P.;THAL, C., TETRAHEDRON LETT., 29,(1988) N 6, 643-646
  作者：BRAYER, J. -L.、ALAZARD, J. -P.、THAL, C.

  DOI：——

  日期：——
• Synergistic phytoceutical compositions
  申请人：Olalde Rangel Angel Jose

  公开号：US20070104728A1

  公开（公告）日：2007-05-10

  Phytoceutical compositions for the prevention and treatment of circulatory disorders, feminine endocrine disorders, and dermal disorders. A specific combination of extracts of plants is taught, as well as principles for varying the formulations based on categorizing plants into one of three groups, Energy, Bio-Intelligence, and Organization and selecting several plants from each group. Such combinations have synergistic effects, with minimal side effects.
• MULTIPLE SCLEROSIS SYNERGISTIC PHYTO-NUTRACEUTICAL COMPOSITION
  申请人：Olalde Jose Angel

  公开号：US20080081046A1

  公开（公告）日：2008-04-03

  A Phytoceutical composition for the prevention and treatment of Multiple Sclerosis (MS) and symptoms is provided. A specific combination of extracts of plants and nutraceuticals is taught, as well as principles for varying the formulations based on categorizing plants into one of three groups, Energy, Bio-Intelligence, and Organization and selecting several plants from each group. Such combinations have synergistic effects, with minimal side effects.