(2-aminoethyl methylsulfoxide)dichloroplatinum (II) | 153177-18-5

• 分子结构分类: 有机化合物 - 有机硫化合物 - 磺酰类
• 英文名称: (2-aminoethyl methylsulfoxide)dichloroplatinum (II)
• CAS: 153177-18-5
• 化学式: C₃H₉Cl₂NOPtS
• 分子量: 373.163
• InChiKey: DCLHXXKHJNVACC-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  potassium tetrachloroplatinate(II) 、 2-(甲基亚磺酰)乙胺 以 水 为溶剂， 生成 (2-aminoethyl methylsulfoxide)dichloroplatinum (II) 、 (2-ammonioethyl methylsulfoxide)trichloroplatinum (II)
  参考文献：
  名称：

  The preparation and characterisation of some aminesulfoxidedichloroplatinum(II) complexes

  摘要：

  A series of compounds designed to bind to GpA sequences of DNA has been prepared and characterised. Procedures have been developed for the syntheses of [Pt{MeS(O)CH2CH2NH2}Cl2] 1 and (2S,SR)- and (2S,SS)-[Pt{MeS(O)CH2CH2CH(CO2Me)NH2}Cl2] 2a, 2b. The crystal structures of 1 and of the two diastereomers, 2a and 2b, have been determined. Crystals of 1 are orthorhombic, space group Pcab, a = 9.405(l), b = 10.847(l), c = 16.170(l) angstrom, Z = 8, R 0.30 for 1410 reflections. Crystals of 2a are orthorhombic, space group P2(1)2(1)2(1), a = 9.738(l), b 10.588(l), c = 11.090(1) angstrom, Z = 4, R = 0.021 for 1382 reflections. Crystals of 2b are orthorhombic, space group P2(1)2(1)2(1), a = 10.977(3), b = 13.738(9), c = 25.24(1) angstrom, Z = 12, R = 0.078 for 1482 reflections. Energy minimisation calculations have been used to develop a force field for a series of dichloroplatinum(ii) sulfoxide complexes.

  DOI：

  10.1039/dt9930003705