| 1238073-94-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• CAS: 1238073-94-3
• 化学式: C₂₇H₃₀O₇S
• 分子量: 498.597
• InChiKey: NRUUUNJONTYUKT-ZJSPYRCASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  35.0
• 可旋转键数：
  10.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  102.29
• 氢给体数：
  2.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  、 甲基磺酰氯 在 吡啶 作用下， 反应 24.0h， 生成
  参考文献：
  名称：

  First synthesis and antiprotozoal activities of divinyl sulfone-modified carbohydrates

  摘要：

  Divinyl sulfone-modified carbohydrates have been synthesized for the first time by reacting easily available carbohydrate epoxides with thioethanol in a regiospecific fashion. One of the modified divinyl sulfones initiated significant cell death in Entamoeba species and the influence of the anomeric configurations on the biological activities of these sugar-derived divinyl sulfones has been highlighted. The most active compound in this series was found to be devoid of any toxicity. (C) 2010 Published by Elsevier Ltd.

  DOI：

  10.1016/j.bmcl.2010.04.056
• 作为产物：
  描述：

  在 magnesium monoperoxyphthalate hexahydrate 作用下， 以 甲醇 为溶剂， 反应 6.0h， 生成
  参考文献：
  名称：

  First synthesis and antiprotozoal activities of divinyl sulfone-modified carbohydrates

  摘要：

  Divinyl sulfone-modified carbohydrates have been synthesized for the first time by reacting easily available carbohydrate epoxides with thioethanol in a regiospecific fashion. One of the modified divinyl sulfones initiated significant cell death in Entamoeba species and the influence of the anomeric configurations on the biological activities of these sugar-derived divinyl sulfones has been highlighted. The most active compound in this series was found to be devoid of any toxicity. (C) 2010 Published by Elsevier Ltd.

  DOI：

  10.1016/j.bmcl.2010.04.056