5-methyl-2-phenyl-4-[(2R,3S,4R,5S)-2,3,4,5-tetrahydroxy-1-(3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-yl)hexyl]-4H-pyrazol-3-one | 1215179-83-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑啉类
• 英文名称: 5-methyl-2-phenyl-4-[(2R,3S,4R,5S)-2,3,4,5-tetrahydroxy-1-(3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-yl)hexyl]-4H-pyrazol-3-one
• CAS: 1215179-83-1
• 化学式: C₂₆H₃₀N₄O₆
• 分子量: 494.547
• InChiKey: SYPQQTCKXUPZIU-AKCRCYLNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.14
• 重原子数：
  36.0
• 可旋转键数：
  8.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  146.26
• 氢给体数：
  4.0
• 氢受体数：
  8.0

反应信息

• 作为产物：
  描述：

  L(-)岩藻糖 、 依达拉奉 在 sodium hydroxide 、 盐酸 作用下， 以 甲醇 、 水 为溶剂， 反应 1.67h， 生成 5-methyl-2-phenyl-4-[(2R,3S,4R,5S)-2,3,4,5-tetrahydroxy-1-(3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-yl)hexyl]-4H-pyrazol-3-one
  参考文献：
  名称：

  Sugar compositional determination of polysaccharides from Dunaliella salina by modified RP-HPLC method of precolumn derivatization with 1-phenyl-3-methyl-5-pyrazolone

  摘要：

  A modified high-performance liquid chromatography method of pre-column derivatization with 1-phenyl-3-methyl-5-pyrazolone (PMP) has been established for high resolution separation and high sensitivity determination of ten monosaccharides simultaneously, which frequently occur in algae polysaccharides. The effects of volume proportion of acetonitrile and pH value of mobile phase (0.1 M phosphate buffer acetonitrile) on retention and separation of the monosaccharide derivatives were investigated with Eclipse XPB-C18 column screened out. The hydrolyzation condition of polysaccharides and derivatization procedure of hydrolysates were also optimized. The modified analysis method was used for the determination of monosaccharide compositions in five polysaccharide fractions isolated from Duanaliella salina. The results showed that PD1 and PD4a were acidic heteropolysaccharide mainly containing glucose and galactose respectively, and PD4a contained sulfated groups; PD2 and PD3 all were a glucan; while PD4b was a complex of polysaccharide linked with nucleic acids by covalent bonds. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carbpol.2010.05.029