tert-butyl 4-[11-[[2-[4-[(2R)-2-hydroxypropyl]triazol-1-yl]acetyl]amino]undecanoyl]piperazine-1-carboxylate | 1192373-49-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: tert-butyl 4-[11-[[2-[4-[(2R)-2-hydroxypropyl]triazol-1-yl]acetyl]amino]undecanoyl]piperazine-1-carboxylate
• CAS: 1192373-49-1
• 化学式: C₂₇H₄₈N₆O₅
• 分子量: 536.715
• InChiKey: BJOVYGTXPVZGDO-JOCHJYFZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  38
• 可旋转键数：
  17
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  130
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Dipeptide Mimics, Libraries Combining Two Dipeptide Mimics with a Third Group, and Methods for Production Thereof
  申请人：Burgess Kevin

  公开号：US20120232268A1

  公开（公告）日：2012-09-13

  Monovalent compounds having moieties comprising at least one amino acid side chain are bound to a core molecule, which also comprises a nucleophilic moiety bound to said core molecule. Monovalent compounds also comprise a macrocyclic ring, a nucleophilic moiety, and a spacer group. Monovalent compounds may be combined into bivalent and trivalent compounds, some of which may have a labeling tag. Methods of production of bivalent compounds and contemplated uses thereof are disclosed.

  含有至少一个氨基酸侧链的单价化合物与核心分子结合，该核心分子还包括与所述核心分子结合的亲核团。单价化合物还包括一个大环环，一个亲核团和一个间隔基团。单价化合物可以组合成双价和三价化合物，其中一些可能具有标记标签。公开了双价化合物的生产方法和拟议的用途。
• DIPEPTIDE MIMICS, LIBRARIES COMBINING TWO DIPEPTIDE MIMICS WITH A THIRD GROUP, AND METHODS FOR PRODUCTION THEREOF
  申请人：Burgess Kevin

  公开号：US20090264315A1

  公开（公告）日：2009-10-22

  Monovalent compounds having moieties comprising at least one amino acid side chain are bound to a core molecule, which also comprises a nucleophilic moiety bound to said core molecule. Monovalent compounds also comprise a macrocyclic ring, a nucleophilic moiety, and a spacer group. Monovalent compounds may be combined into bivalent and trivalent compounds, some of which may have a labeling tag. Methods of production of bivalent compounds and contemplated uses thereof are disclosed.
• US9562023B2
  申请人：——

  公开号：US9562023B2

  公开（公告）日：2017-02-07