μ-[dichloro(cis-cyclooctene)palladium(II)]2 | 12148-19-5

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: μ-[dichloro(cis-cyclooctene)palladium(II)]2
• 英文别名: di-μ-chlorodichlorobis(η(2)-cyclooctene)dipalladium(II)；cyclooctene;dichloropalladium
• CAS: 12148-19-5
• 化学式: C₁₆H₂₈Cl₄Pd₂
• 分子量: 575.05
• InChiKey: QZTTXILRYMXUKE-BJTMLYKVSA-J

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  μ-[dichloro(cis-cyclooctene)palladium(II)]2 、 二乙基(3-吡啶基)-硼烷 在 H₂O 作用下， 以 二氯甲烷 为溶剂， 以42%的产率得到
  参考文献：
  名称：

  氨基硼化合物与钯铂配合物的反应

  摘要：

  3-NH2C6H4B(OH)2 (1, APBA) 与 [MCl4]2- (M = Pd, Pt) 反应生成含硼酸的复合物 MCl2(APBA)2 (M = Pd, 2; M = Pt , 3)。将 1 添加到 [PdCl2(COE)]2 (COE = η2-C8H14) 最终生成 PdCl2(APBA)2 (2)。频哪醇衍生物 PdCl2(APBpin)2 (5, pin = O2C2Me4) 通过 X 射线衍射研究表征。5个晶体为单斜晶系，a = 13.836(5)，b = 14.937(5)，c = 11.287(5) A，β = 99.042(9)°，Z = 2，空间群为 P21/c。单烯烃配合物 PtCl2(COE)(APBA) (8) 和 PtCl2(COE)(APBpin) (9) 分别通过将 APBA 和 APBpin 添加到 [PtCl2(COE)]2 中而产生。2-NMe2CH2C6H4B(OH)2

  DOI：

  10.1139/v99-106
• 作为产物：
  描述：

  顺-环辛烯 、 palladium dichloride 在 NaCl 、 NaOAc 作用下， 以 溶剂黄146 为溶剂， 以94.3%的产率得到μ-[dichloro(cis-cyclooctene)palladium(II)]2
  参考文献：
  名称：

  η³-Allylpalladium Complexes from Medium-Ring Cycloalkenes

  摘要：

  The dimeric eta(3)-allylpalladium chloride complexes formed from various cycloalkenes (C-7-C-13) and some methyl-and tert-butyl-substituted cycle alkenes have be en characterized by H-1 and C-13 NMR spectroscopy and in selected cases by X-ray crystallography. The formation of syn and anti isomers in the larger ring systems is demonstrated, and complexes with a rearranged ring system are formed from tert-butylcyclodecene and tert-butylcyclododecene. The sesquiterpene, carophyllene, is shown to form an eta(3)-allyl exocyclic complex, exclusively from the (E)-double bond. Cis and trans isomers, with respect to allyl group orientation in these halo-bridged dimers, have been identified by low-temperature (190K) NMR spectroscopy, and their interconversion (Delta G(double dagger) approximate to 11 kcal/mol) is considered to involve a "cubic" eta(3)-allylpalladium chloride tetramer.

  DOI：

  10.1021/om971132c

文献信息

• The phosphinoboration of 2-diphenylphosphino benzaldehyde and related aldimines
  作者：Meagan B. Kindervater、Justin F. Binder、Samuel R. Baird、Christopher M. Vogels、Stephen J. Geier、Charles L.B. Macdonald、Stephen A. Westcott

  DOI：10.1016/j.jorganchem.2018.11.001

  日期：2019.2

  reactions proceed selectively to give one new product where the phosphide fragment has added to the aldehyde (or imine) carbon atom and the electron-deficient boron group has added to the electron-rich heteroatom. Preliminary studies show these new compounds can ligate to Pd(II) and Pt(II) metal centres. These novel metal complexes, as well as the organic soluble [MCl2(coe)]2 (M = Pd, Pt, coe = cis-cyclooctene)

  我们研究了向2-二苯基膦基苯甲醛（2-Ph 2 PC 6 H 4 C（O）H）添加简单的膦基硼酸酯Ph 2 PBpin（pin = 1,2-O 2 C 2 Me 4）以及相关方法醛亚胺衍生物（2-Ph 2 PC 6 H 4C（NR）H）作为产生带有路易斯酸Bpin侧基的独特二膦配体的简单有效策略。这些反应选择性地进行，得到一种新产物，其中磷化物片段已添加到醛（或亚胺）碳原子上，而缺电子的硼基团已添加到了富电子杂原子上。初步研究表明，这些新化合物可以连接到Pd（II）和Pt（II）金属中心。这些新型金属络合物以及有机可溶[MCl 2（coe）] 2（M = Pd，Pt，coe = 顺式-环辛烯）化合物已被证明是有效的预催化剂，可用于炔酸环化反应对应的exo-挖环内酯。采用这些金属络合物的反应还产生了不同寻常的内挖式环内酯，这些环内酯传统上在这些环化反应中没有观察到。例如，4-戊酸的反应还提供
• Synthesis and reactivity of palladium and platinum diimine complexes containing boronate esters
  作者：Arienne S King、Liliya G Nikolcheva、Christopher R Graves、Anna Kaminski、Christopher M Vogels、Robert HE Hudson、Robert J Ireland、Stephen J Duffy、Stephen A Westcott

  DOI：10.1139/v02-145

  日期：2002.9.1

  Condensation of α-diketones (2,3-butanedione, benzil, and acenaphthenequinone) with 3-H₂NC₆H₄Bpin (pin = 1,2-O₂C₂Me₄) gave the corresponding boron-containing α-diimines. The addition of these ligands to [MCl₂(coe)]₂ (coe = cis-cyclooctene, M = Pd or Pt) gave complexes of the type cis-MCl₂(α-diimine) in moderate to high yields. The platinum complexes have been examined for their ability to bind to DNA using enzyme digest studies. These complexes were found to bind to single-stranded DNA as well as, or better than, the non-boron containing controls, and showed binding similar to that of cisplatin (cis-PtCl₂(NH₃)₂).Key words: boronate esters, diazabutadienes, DNA-binding, platinum.

  α-二酮（2,3-丁二酮、苯甲酮和芴醌）与3-H₂NC₆H₄Bpin（pin = 1,2-O₂C₂Me₄）发生缩合反应，得到相应的含硼α-二亚胺。将这些配体加入到[MCl₂(coe)]₂（coe = 顺式-环辛烯，M = Pd或Pt）中，以中等至高收率得到cis-MCl₂(α-二亚胺)型配合物。铂配合物已经被检测其通过酶消化研究结合到DNA的能力。发现这些配合物与单链DNA结合的能力与或优于非含硼对照物，并显示出与顺式铂铂胺（cis-PtCl₂(NH₃)₂）相似的结合。关键词：硼酸酯、二氮丁二烯、DNA结合、铂。