bis(1-mercapto-2-ethanolato-S)mercury(II) | 64762-03-4

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: bis(1-mercapto-2-ethanolato-S)mercury(II)
• 英文别名: bis(2-hydroxyethanethiolato)mercury(II)；2-mercapto-ethanol; mercury (II)-compound；2-Mercapto-aethanol; Quecksilber(II)-Verbindung；Bis-(2-hydroxy-aethylthio)-quecksilber
• CAS: 64762-03-4
• 化学式: C₄H₁₀HgO₂S₂
• 分子量: 354.844
• InChiKey: HYYFNFQPBTZRMF-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.48
• 重原子数：
  5.0
• 可旋转键数：
  1.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.23
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  氰化汞 、 2-巯基乙醇 以 乙醇 为溶剂， 以95%的产率得到bis(1-mercapto-2-ethanolato-S)mercury(II)
  参考文献：
  名称：

  Mercury(II) and organomercury(II) complexes of thiols and dithiols, including british anti-lewisite

  摘要：

  DOI：

  10.1016/s0020-1693(00)93859-3

文献信息

• Revealing aggregation-induced emission effect of imidazolium derivatives and application for detection of Hg2+
  作者：Shuai Huang、Tang Gao、Anyao Bi、Xiaozheng Cao、Bin Feng、Min Liu、Tao Du、Xueping Feng、Wenbin Zeng

  DOI：10.1016/j.dyepig.2019.107830

  日期：2020.1

  As the steric hindrance of the CFG increases, the AIE characteristic of the derivative also becomes apparent. With the assistance of the thioacetal unit, BMIBD can act as an outstanding probe for the detection of Hg2+ with high sensitivity and selectivity. A series of characterizations were implemented to prove the unique response mechanism of BMIBD toward mercury ions, including optical behavior

  尽管在溶液中具有高发射率，但是4-（4,5-双（4-甲氧基苯基）-1H-咪唑-2-基）苯甲醛（BMI）分子的聚集通常会导致荧光猝灭。为了克服聚集引起的猝灭（ACQ）的缺点，已发现BMI的氮原子中的咪唑取代基作为构象官能团（CFG），以转变聚集诱导的发射（AIE）效应。CFG的引入不仅会导致分子内旋转（RIR）效应受到限制，而且还会削弱分子的共面性。结果，具有ACQ效果的BMI转换为BMI具有AIE效果。随着CFG的位阻增加，衍生物的AIE特性也变得明显。借助硫缩醛单元，BMIBD可以作为出色的探针以高灵敏度和高选择性检测Hg 2+。进行了一系列表征以证明BMIBD对汞离子的独特反应机理，包括光学行为研究，质量分析和1 H NMR研究。此外，检测极限低至36 nM。利用此AIE探针BMIBD的优异光学性能，对用于Hg 2+检测的即时检验（POCT）进行了进一步研究。同时，BMIBD为实际水样
• Preparation and 199Hg NMR study of some mercury(II) thiolate complexes
  作者：Laurence Carlton、David White

  DOI：10.1016/s0277-5387(00)86801-1

  日期：1990.1
• Sensitive Water-Soluble Fluorescent Probe Based on Umpolung and Aggregation-Induced Emission Strategies for Selective Detection of Hg²⁺ in Living Cells and Zebrafish
  作者：Tang Gao、Xueyan Huang、Shuai Huang、Jie Dong、Kai Yuan、Xueping Feng、Tingting Liu、Kunqian Yu、Wenbin Zeng

  DOI：10.1021/acs.jafc.8b06895

  日期：2019.2.27

  Using Hg2+-induced umpolung reaction and aggregation induced emission (AlE), we have rationally developed a water-soluble fluorescent probe 2,2'-(((4-(4,5-bis(4-methoxyphenyl)-1-phenyl-1H-imidazol-2-yl)phenyl)methylene)bis-(sulfanediyl))diethanol(MPIPBS) for Hg2+ detection. MPIPBS was found to have high selectivity and sensitivity toward Hg2+ detection. The mechanism of MPIPBS response to Hg2+ was verified by H-1 NMR titration, HPLC, and HAMS spectroscopy. The detection limit was examined to be 1.45 nM, which is lower than most reported probes for Hg2+. Taking advantage of excellent optical properties of AlEgen, a paper based sensor for Hg2+ detection was fabricated by immobilizing the MPIPBS on Waterman test paper. Meanwhile, MPIPBS showed satisfactory analytical performance in real water and urine samples. Further, thanks to the high water solubility, cell membrane permeability and low cytotoxicity, MPIPBS was further used to detect Hg2+ both in living cells and zebrafish. We anticipate that the prepared probe was available to detect Hg2+ in environment and biosamples.