N-Stearoylsphingosine | 54336-64-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 鞘脂
• 英文名称: N-Stearoylsphingosine
• 英文别名: N-(1,3-dihydroxyoctadec-4-en-2-yl)octadecanamide
• CAS: 54336-64-0
• 化学式: C₃₆H₇₁NO₃
• 分子量: 565.965
• InChiKey: VODZWWMEJITOND-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13.9
• 重原子数：
  40
• 可旋转键数：
  32
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  69.6
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  sphingomyelin 在 phospholipase C type I 、 水 作用下， 以 乙醇 、 正己烷 、 乙酸乙酯 为溶剂， 生成 N-Stearoylsphingosine
  参考文献：
  名称：

  Effect of Laser and LED on Enzymatic Production of Ceramide

  摘要：

  AbstractAn enzyme (Phospholipase C Type I from Clostridium perfringens) was exposed to 0–810 J cm−2 of energy using laser light at wavelengths 808, 532, 1064 and 1342 nm and two LED light sources at wavelengths 810 and 640 nm. Enzyme responses were evaluated by measuring ceramide concentration using high performance thin‐layer chromatography (HPTLC) at 0.5, 1, 2, 3, 4, 6, 17, 24 h after irradiation. The duration of effect was evaluated from the experimental data. The results show that enzyme activity can be increased by using both laser and LED sources whose wavelength is located within a certain range. The effect depends on the energy and wavelength of the light. The increase in enzyme activity continued for about 4 h after irradiation. This study shows that the duration of irradiation should be included as one of the main laser parameters when reporting on the effects of laser irradiation on enzymes. We also find that laser sources and LED sources have the same effect on enzyme activity if the wavelength and absorbed energy are equal.

  DOI：

  10.1111/j.1751-1097.2010.00820.x

文献信息

• Effect of Laser and LED on Enzymatic Production of Ceramide
  作者：Hongyu Zhang、Long Zhang、Peter Tidemand-Lichtenberg、Preben Buchhave、Xuebing Xu、Yingxin Li

  DOI：10.1111/j.1751-1097.2010.00820.x

  日期：2011.1

  AbstractAn enzyme (Phospholipase C Type I from Clostridium perfringens) was exposed to 0–810 J cm−2 of energy using laser light at wavelengths 808, 532, 1064 and 1342 nm and two LED light sources at wavelengths 810 and 640 nm. Enzyme responses were evaluated by measuring ceramide concentration using high performance thin‐layer chromatography (HPTLC) at 0.5, 1, 2, 3, 4, 6, 17, 24 h after irradiation. The duration of effect was evaluated from the experimental data. The results show that enzyme activity can be increased by using both laser and LED sources whose wavelength is located within a certain range. The effect depends on the energy and wavelength of the light. The increase in enzyme activity continued for about 4 h after irradiation. This study shows that the duration of irradiation should be included as one of the main laser parameters when reporting on the effects of laser irradiation on enzymes. We also find that laser sources and LED sources have the same effect on enzyme activity if the wavelength and absorbed energy are equal.