7,8-Dimethyl-9-<1,3-benzodioxolyl-(5)>-6,7,8,9-tetrahydro-naphtho<1,2-d>-1,3-dioxol | 3684-40-0

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 芳基四氢萘木脂素
• 英文名称: 7,8-Dimethyl-9-<1,3-benzodioxolyl-(5)>-6,7,8,9-tetrahydro-naphtho<1,2-d>-1,3-dioxol
• 英文别名: 7,8-Dimethyl-9-<1,3-benzodioxolyl-(5)>-6,7,8,9-tetrahydro-naphtho<1,2-d>-1,3-dioxol, 'Otobain', 'Otobit'；9-benzo[1,3]dioxol-5-yl-7,8-dimethyl-6,7,8,9-tetrahydro-naphtho[1,2-d][1,3]dioxole；Otobaine；9-(1,3-benzodioxol-5-yl)-7,8-dimethyl-6,7,8,9-tetrahydrobenzo[g][1,3]benzodioxole
• CAS: 3684-40-0；3738-01-0
• 化学式: C₂₀H₂₀O₄
• 分子量: 324.376
• InChiKey: HTUIKPYRGODLDO-UHFFFAOYSA-N

物化性质

• 熔点：
  137-138°
• 比旋光度：
  D -40.5° (c = 3.2 in chloroform)
• 沸点：
  424.3±45.0 °C(Predicted)
• 密度：
  1.234±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  24
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Topical formulations and methods of use
  申请人：Morariu Marius

  公开号：US20060216251A1

  公开（公告）日：2006-09-28

  A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles and loss of elasticity. Preferred components include R-lipoic acid or R-dihydrolipoic acid, acetyl-1-carnitine, and 1-carnosine.

  本发明提供了一种外用组合物，该组合物包含硫辛酸、肉毒碱和肉毒碱，并以适合外用的载体形式存在，还提供了一种治疗皮肤的方法。本组合物有助于改善以皱纹和失去弹性为特征的老化皮肤的外观。优选成分包括 R-硫辛酸或 R-二氢硫辛酸、乙酰基-1-肉碱和 1-肉碱。
• Methods of Treating Skin
  申请人：Morariu Marius

  公开号：US20100272790A1

  公开（公告）日：2010-10-28

  A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles and loss of elasticity. Preferred components include R-lipoic acid or R-dihydrolipoic acid, acetyl-l-carnitine, and l-carnosine.
• METHODS OF TREATING SKIN
  申请人：Tracie Martyn International, Inc.

  公开号：US20140155961A1

  公开（公告）日：2014-06-05

  A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles and loss of elasticity. Preferred components include R-lipoic acid or R-dihydrolipoic acid, acetyl-l-carnitine, and l-carnosine.
• Compositions, Methods, and Medical Compositions for Treatment of and Maintaining the Health of the Liver
  申请人：Unigen, Inc.

  公开号：US20170035829A1

  公开（公告）日：2017-02-09

  Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Myristica extract, at least one Astragalus extract, and at least one Schizandra extract. Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Myristica extract enriched for one or more lignans, including phenylpropanoids, dimers and polymers, at least one Astragalus extract enriched for one or more polysaccharides and triterpenoids, and at least one Schizandra extract enriched for one or more lignans and organic acids. Compositions and methods for treatment of and maintaining the health of the liver are disclosed that include a mixture of plant extracts, wherein the plant extracts comprise at least one Myristica extract, at least one Astragalus extract, and at least one Poria extract.
• US7776915B2
  申请人：——

  公开号：US7776915B2

  公开（公告）日：2010-08-17