5,7-二氯-4-硝基苯并[c][1,2,5]噁二唑 | 15944-78-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶二唑类
• 中文名称: 5,7-二氯-4-硝基苯并[c][1,2,5]噁二唑
• 英文名称: 5,7-dichloro-4-nitro-2,1,3-benzoxadiazole
• 英文别名: 4,6-dichloro-7-nitrobenzofurazan；4,6-Dichlor-7-nitro-benzofurazan；5,7-dichloro-4-nitro-benzo[1,2,5]oxadiazole
• CAS: 15944-78-2
• 化学式: C₆HCl₂N₃O₃
• mdl: MFCD00460659
• 分子量: 233.998
• InChiKey: SCVFVTLATGCDGT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  84.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  5,7-二氯-4-硝基苯并[c][1,2,5]噁二唑 在 氢氧化钾 作用下， 生成 4,6-dihydroxy-7-nitrobenzofurazan
  参考文献：
  名称：

  Tsentovskii, V. M.; Evgen'ev, M. I.; Petukhova, L. V., Journal of general chemistry of the USSR, 1986, vol. 56, p. 1020 - 1023

  摘要：

  DOI：

文献信息

• Agent and method for dyeing keratin fibers
  申请人：——

  公开号：US20030070239A1

  公开（公告）日：2003-04-17

  The present invention relates to a fiber-dyeing agent (A) prepared by mixing two components (A1) and (A2), said agent being characterized in that component (A1) contains at least one compound of formula (I) 1 wherein X denotes a halogen atom, a methoxy group or an ethoxy group; Y denotes an oxygen atom, a sulfur atom or a selenium atom; R1 and R2 are equal or different and independently of each other denote hydrogen, a halogen atom, a (C 1 -C 4 )-alkyl group, a halogen-substituted (C 1 -C 4 )-alkyl group, a (C 1 -C 4 )-alkoxy group, a nitro group, an acetamido group or an NR a R b group, wherein the R a and R b groups are equal or different and independently of each other denote hydrogen, a (C 1 -C 4 )-alkyl group, an optionally substituted aromatic carbon ring or a (C 1 -C 4 )-alkanecarbonyl group, or R a and R b together with the nitrogen atom form a heterocyclic (C 3 -C 6 ) group, and component (A2) contains at least one compound from the group consisting of amines, aminonitrobenzenes and phenols; to a method for dyeing hair by use of said agent, and to a multicomponent kit.

  本发明涉及一种纤维染料剂（A），其由混合两个组分（A1）和（A2）制备而成，其中该剂特征在于组分（A1）包含至少一个式（I）1的化合物，其中X表示卤素原子、甲氧基或乙氧基；Y表示氧原子、硫原子或硒原子；R1和R2相等或不同且独立地表示氢、卤素原子、（C1-C4）烷基、卤素取代的（C1-C4）烷基、（C1-C4）烷氧基、硝基、乙酰胺基或NRaRb基，其中Ra和Rb基相等或不同且独立地表示氢、（C1-C4）烷基、可选取代的芳环碳环或（C1-C4）烷基羰基基团，或Ra和Rb与氮原子一起形成杂环（C3-C6）基团，而组分（A2）包含至少一种来自胺、氨基硝基苯和酚的化合物组成的群体中的化合物；以及一种使用该剂染发的方法和多组分套装。
• Method for producing optically active compound
  申请人：——

  公开号：US20020006645A1

  公开（公告）日：2002-01-17

  The present invention provides a method for industrially advantageously producing (S)-4-hydroxy-2-ketoglutaric acid and for producing compounds which are formed by biosynthesis from the precursor (S)-4-hydroxy-2-ketoglutaric acid, for example, for producing the compounds (2S,4S)-4-hydroxy-L-glutamic acid and (2S,4S)-4-hydroxy-L-proline, using a recombinant microorganism carrying a recombinant DNA harboring the DNA fragment encoding 4(S)-4-hydroxy-2-ketoglutaric acid aldolase gene.

  本发明提供了一种工业上优势生产(S)-4-羟基-2-酮戊二酸的方法，并利用携带重组DNA的重组微生物生产由前体(S)-4-羟基-2-酮戊二酸生物合成的化合物，例如，用于生产化合物(2S,4S)-4-羟基-L-谷氨酸和(2S,4S)-4-羟基-L-脯氨酸，所述重组DNA携带编码4(S)-4-羟基-2-酮戊二酸醛缩酶基因的DNA片段。
• Process for producing cis-3-hydroxy-L-proline
  申请人：KYOWA HAKKO KOGYO CO., LTD.

  公开号：EP0645457A2

  公开（公告）日：1995-03-29

  Provided is a process for industrially producing cis-3-hydroxy-L-proline useful as a raw material for medicines or as an additive to foods. L-proline is converted into cis-3-hydroxy-L-proline in the presence of an enzyme source which is derived from a microorganism belonging to the genus Streptomyces or Bacillus and which catalyzes hydroxylation of L-proline into cis-3-hydroxy-L-proline, a divalent iron ion and 2-ketoglutaric acid, in an aqueous medium, and the produced cis-3-hydroxy-L-proline is recovered from the aqueous medium. Also provided is a novel enzyme L-proline-3-hydroxylase, which is useful for the process.

  本发明提供了一种工业化生产可用作药物原料或食品添加剂的顺式-3-羟基-L-脯氨酸的工艺。在一种酶源的存在下，L-脯氨酸被转化成顺式-3-羟基-L-脯氨酸，该酶源来自一种属于链霉菌属或芽孢杆菌属的微生物，它在水介质中催化 L-脯氨酸羟化成顺式-3-羟基-L-脯氨酸、二价铁离子和 2-酮戊二酸，并从水介质中回收生成的顺式-3-羟基-L-脯氨酸。此外，还提供了一种新型 L-脯氨酸-3-羟化酶，可用于该工艺。
• ——
  作者：F. S. Levinson、S. I. Efimov、B. I. Buzykin、A. T. Gubaidullin、D. B. Krivolapov、I. A. Litvinov

  DOI：10.1023/a:1015017931597

  日期：——

  The molecular and crystal structures of 5,7-dichloro-4-nitro-2,1,3-benzoxadiazole and products of its reactions with hexamethyleneimine and dimethylamine were established by X-ray diffraction analysis. The molecular structures and the systems of hydrogen bonds in the crystals of these compounds are discussed.
• L-proline-3-hydroxylase and process for producing cis-3-hydroxy-L-proline
  申请人：KYOWA HAKKO KOGYO CO., LTD.

  公开号：EP0645457B1

  公开（公告）日：1998-04-01