Ethoxytriphenyl carbinol | 83796-10-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: Ethoxytriphenyl carbinol
• 英文别名: [ethylperoxy(diphenyl)methyl]benzene
• CAS: 83796-10-5
• 化学式: C₂₁H₂₀O₂
• 分子量: 304.389
• InChiKey: HQONPLBKQHQADR-UHFFFAOYSA-N

物化性质

• 沸点：
  411.3±44.0 °C(Predicted)
• 密度：
  1.092±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  三苯基甲基溴 、 二乙基汞 在 air 作用下， 以 1,2-二氯乙烷 为溶剂， 以44%的产率得到Ethoxytriphenyl carbinol
  参考文献：
  名称：

  Uglova, E. V.; Makhaev, V. D.; Reutov, O. A., Journal of Organic Chemistry USSR (English Translation), 1982, vol. 18, # 8, p. 1386 - 1389

  摘要：

  DOI：

文献信息

• Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and therapeutics produced therewith
  申请人：Rohm and Haas Company

  公开号：EP1447408A1

  公开（公告）日：2004-08-18

  The present invention relates to a process for making a biologically active substance or therapeutic agent free of a chlorotrityl chloride linker-resin. The process includes reacting an activated amino acid or activated amino acid derivative with a substituted or unsubstituted trityl alcohol resin to obtain a resin-CT-AA product; and, reacting the resin-CT-AA product with other building blocks of the biologically active substance or therapeutic agent to obtain said biologically active substance or therapeutic. A product created by this process is also provided herein. The invention is particularly useful to create T-20 and T-1249 therapeutics.

  本发明涉及一种制造不含氯化三苯酯连接体-树脂的生物活性物质或治疗剂的工艺。该工艺包括使活化氨基酸或活化氨基酸衍生物与取代或未取代的三苯甲醇树脂反应，得到树脂-CT-AA 产物；以及使树脂-CT-AA 产物与生物活性物质或治疗剂的其他结构单元反应，得到所述生物活性物质或治疗剂。本发明还提供了通过该工艺制作的产品。本发明尤其适用于制造 T-20 和 T-1249 治疗剂。
• Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and biologically active substances and therapeutics produced therewith
  申请人：——

  公开号：US20040158037A1

  公开（公告）日：2004-08-12

  The present invention relates to a process for making a biologically active substance or therapeutic agent free of a chlorotrityl chloride linker-resin. The process includes reacting an activated amino acid or activated amino acid derivative with a substituted or unsubstituted trityl alcohol resin to obtain a resin-CT-AA product; and, reacting the resin-CT-AA product with other building blocks of the biologically active substance or therapeutic agent to obtain said biologically active substance or therapeutic. A product created by this process is also provided herein. The invention is particularly useful to create T-20 and T-1249 therapeutics.
• Uglova, E. V.; Makhaev, V. D.; Reutov, O. A., Journal of Organic Chemistry USSR (English Translation), 1982, vol. 18, # 8, p. 1386 - 1389
  作者：Uglova, E. V.、Makhaev, V. D.、Reutov, O. A.

  DOI：——

  日期：——