1,2-Bis-(methylsulfinyl)-ethan | 10349-04-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 亚砜
• 英文名称: 1,2-Bis-(methylsulfinyl)-ethan
• 英文别名: 2,5-Dithiahexan-2,5-dioxid；1,2-Bis(methylsulfinyl)ethane
• CAS: 10349-04-9
• 化学式: C₄H₁₀O₂S₂
• 分子量: 154.254
• InChiKey: JHKDMTXEOGSFBK-UHFFFAOYSA-N

物化性质

• 沸点：
  445.5±28.0 °C(Predicted)
• 密度：
  1.358±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  72.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,2-Bis-(methylsulfinyl)-ethan 在 potassium permanganate 作用下， 生成 1,2-bis(methylsulphonyl)ethane
  参考文献：
  名称：

  Bruun et al., Svensk Papperstidning (1943), 1950, vol. 53, p. 440

  摘要：

  DOI：

文献信息

• Sulphur ligand metal complexes. Part 6. Copper complexes of 2,5-dithiahexane and 3,6-dithiaoctane
  作者：Eric W. Ainscough、Andrew M. Brodie、Kevin C. Palmer

  DOI：10.1039/dt9760002375

  日期：——

  dithioethers 2,4-dithiahexane (dth) and 3,6-dithiaoctane (dto) form the following complexes, some of which have been previously reported, with CuII and CuI: Cu(BF4)2L2 and CuX2L (L = dth or dto, X = Cl or Br); [CuL2]X (L = dth or dto. X = SF,: L = dth, X = ClO4); CuXL (L = dth, X = Cl, Br, or I; L = dto, X = I or SCN); and (CuCl)2L (L = dto, X = Cl or Br). The complexes have been characterized by a variety

  二硫醚2,4-二硫代己烷（dth）和3,6-二硫代辛烷（dto）与Cu II和Cu I形成以下配合物，其中一些已被报道：Cu（BF 4）2 L 2和CuX 2 L（L = dth或dto，X = Cl或Br）；[CuL 2 ] X（L ＝ dth或dto。X＝ SF，：L ＝ dth，X ＝ ClO 4）；CuXL（L = dth，X = Cl，Br或I； L = dto，X = I或SCN）；和（CuCl）2L（L = dto，X = Cl或Br）。复合物已通过多种物理化学技术进行了表征，并在可能的地方提出了结构。讨论了铜-硫键的性质，并得出结论，硫醚不会与Cu II形成明显的π键。螯合的硫醚配体容易被取代，例如从CuCl 2 L（L = dth或dto）和CuCl（dth）取代。通过各种配体（例如吡啶，吡咯烷，2,2'-联吡啶基，乙二胺，PPh 3，PMe 3 S和Na [S 2 PMe
• The chemistry of quadrivalent lanthanoids. Part 2. Preparation and properties of cerium tetrachloride complexes and a comparison with their uranium analogues
  作者：John Barry、Jan G. H. du Preez、Thomas I. Gerber、Annelie Litthauer、Hans E. Rohwer、Bernardus J. van Brecht

  DOI：10.1039/dt9830001265

  日期：——

  Cerium tetrachloride complexes, viz. [CeCl4L2] and [CeCI4L] where L = a uni- or bi-dentate arsine oxide, a phosphine oxide, a sulphoxide, or an amide, have been prepared. The thermal degradation behaviour of the solids could be divided into three patterns, one of which consists of loss of a chlorine atom only. It was indicated that [CeCI4(ipae)2] could act as a substitute for the thermally unstable

  四氯化铈配合物，即。已经制备了[CeCl 4 L 2 ]和[CeCl 4 L]，其中L ＝单齿或双齿氧化砷，氧化膦，亚砜或酰胺。固体的热降解行为可以分为三种模式，其中一种仅由氯原子的损失组成。指出[CeCl 4（ipae）2 ]可以代替热不稳定的CeCl 4进行溶液研究[ipae = 1-（二异丙基氨基）乙醛。[ CeCl 4（ipae）2 ]和Cs 2 [CeCI 6 ]溶液的分解速率研究]在不同的溶剂中表示分解反应相对于铈（IV）是一阶的，并且其反应速率大约与溶剂的供体数成正比。亚硫酰氯中的溶液可以无限期稳定。在配位行为，红外光谱，非水电导行为和溶剂镜性质方面，将研究的化合物与其铀（IV）类似物进行了比较。在加入CeCl 4和UCI 4个络合物证明几乎在所有方面非常类似，不同之处在于这些铈（IV）更solvoscopic。铈（IV）与铀（IV）之间的一些区别）可能最好用4 f和5 f金属字符之间的差异而不是尺寸差异来解释。
• Disulfoxide complexes with lanthanum perchlorate
  作者：Arden P. Zipp、Sybil G. Zipp

  DOI：10.1016/0022-1902(80)80013-3

  日期：1980.1

  The synthesis and characterization of the complexes between La(ClO4)3 and eleven disulfoxides with the formula RS(O) (CH2)xS(O)R are reported. In all cases, the lathanum ions is eight-coordinated and bonded to the sulfoxide moieties via the oxygen atom.

  报道了La（ClO 4）3和十一种具有式RS（O）（CH 2）x S（O）R的二亚砜之间的配合物的合成和表征。在所有情况下，镧离子都是八配位的，并通过氧原子键合至亚砜部分。
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Sc: MVol.D4, 1.1.16, page 45 - 46
  作者：

  DOI：——

  日期：——
• Bidentate Sulfoxide Complexes of Ruthenium(II) and Their Preliminary Biological Assessment <i>in Vitro</i>
  作者：Donald T. T. Yapp、Steven J. Rettig、Brian R. James、Kirsten A. Skov

  DOI：10.1021/ic9606486

  日期：1997.11.1

  The complexes trans-RuCl2(BMSE)(2) (1), cis-RuCl2(BESE)(2) (2), trans-RuCl2(BPSE)(2) (3), and cis-RuCl2(BMSP)(2) (4) have been synthesized and characterized, including X-ray analyses [BMSE = 1,2-bis(methylsulfinyl)ethane, BESE = 1,2-bis(ethylsulfinyl)ethane, BPSE = 1,2-bis(propylsulfinyl)ethane, and BMSP = 1,3-bis(methylsulfinyl)propane]. Crystal data are as follows: 1 . H2O, triclinic, P1, a 8.863(1) Angstrom, b = 14.462(3) Angstrom, c 7.543(1) Angstrom, alpha = 103.39(1)degrees, beta = 113.31(1)degrees, gamma = 77.23(1)degrees, 2=2; 2 . MeOH, triclinic, , n 14.858(2) Angstrom, b = 16.732(3) Angstrom, c 10.609(2) Angstrom, alpha 105.14(2)degrees, beta 93.34(2)degrees, gamma = 115.91(1)degrees, Z= 4; 3, orthorhombic, Aba2, a = 14.894(1) Angstrom, b = 7.501(1) Angstrom, c = 21.911(2) Angstrom, Z = 4; 4, orthorhombic, Pcab, a = 15.257(3) Angstrom, b = 18.138(2) Angstrom, c = 13.395(2) Angstrom, Z = 8. The structures were solved by the Patterson method and were refined by full-matrix least-squares procedures to R = 0.026, 0.026, 0.029, and 0.031 for 10461, 8952, 1594, and 5694 reflections with I > 3 sigma(I), for 1-4, respectively. Preliminary in vitro experiments with Chinese hamster ovary cells indicate that the trans-complexes accumulate in the cells and bind to DNA to a greater degree than the cis-complexes.