Adipinsaeuredithiophenylester | 41117-90-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯硫酚酯
• 英文名称: Adipinsaeuredithiophenylester
• 英文别名: di-S-phenyl thioadipate；1,6-dithio-adipic acid S,S'-diphenyl ester；1,6-Dithio-adipinsaeure-S,S'-diphenylester；S~1~,S~6~-Diphenyl hexanebis(thioate)；1-S,6-S-diphenyl hexanebis(thioate)
• CAS: 41117-90-2
• 化学式: C₁₈H₁₈O₂S₂
• 分子量: 330.472
• InChiKey: VESNZOIGQGPYFP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  22
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  84.7
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  己二酸 、 苯硫酚 生成 Adipinsaeuredithiophenylester
  参考文献：
  名称：

  从羧酸和硫醇轻松合成羧酸硫醇酯

  摘要：

  通过硫醇与由游离羧酸和对甲苯磺酸2-氟-1-甲基吡啶鎓原位形成的酰氧基吡啶鎓盐反应，以良好的产率制备各种硫羟酸酯。

  DOI：

  10.1246/cl.1976.741

文献信息

• Method for Producing Carboxylic Acid Thioester
  申请人：Mitsubishi Chemical Corporation

  公开号：US20180265461A1

  公开（公告）日：2018-09-20

  According to the present invention, there is provided a method for producing carboxylic acid thioester, comprising reacting a compound represented by the following formula (I), carboxylic acid and thiol in the presence of a catalyst including at least one Group 2 metal compound. The production method is a production method which is simple in reaction operation, which places a small load on the environment and the human body and which enables carboxylic acid thioester to be catalytically obtained at a high yield even at a normal temperature and a normal pressure (25° C., 1 atm). In the formula (I), R 1 and R 2 each independently represent a hydrocarbon group having 1 to 20 carbon atoms.

  根据本发明，提供了一种生产羧酸硫酯的方法，包括在至少包括一种第2族金属化合物的催化剂存在下，将下式（I）所代表的化合物、羧酸和硫醇反应。该生产方法是一种在反应操作上简单、对环境和人体负荷小的生产方法，即使在常温和常压（25°C，1大气压）下也能以高产率催化获得羧酸硫酯。在式（I）中，R1和R2各自独立地表示具有1至20个碳原子的碳氢基团。
• THE REACTION OF TRIMETHYLSILYL SULFIDES WITH CARBOXYLIC ESTERS. A CONVENIENT METHOD FOR THE PREPARATION OF THIOLESTERS
  作者：Teruaki Mukaiyama、Takeshi Takeda、Kunio Atsumi

  DOI：10.1246/cl.1974.187

  日期：1974.2.5

  In the presence of AlCl3, trimethylsilyl sulfides react with carboxylic esters to give the corresponding thiolesters in high yields.

  在 AlCl3 存在下，三甲基甲硅烷基硫化物与羧酸酯反应以高产率得到相应的硫醇酯。
• Method for producing carboxylic acid thioester
  申请人：Mitsubishi Chemical Corporation

  公开号：US10377706B2

  公开（公告）日：2019-08-13

  According to the present invention, there is provided a method for producing carboxylic acid thioester, comprising reacting a compound represented by the following formula (I), carboxylic acid and thiol in the presence of a catalyst including at least one Group 2 metal compound. The production method is a production method which is simple in reaction operation, which places a small load on the environment and the human body and which enables carboxylic acid thioester to be catalytically obtained at a high yield even at a normal temperature and a normal pressure (25° C., 1 atm). In the formula (I), R1 and R2 each independently represent a hydrocarbon group having 1 to 20 carbon atoms.

  根据本发明，提供了一种生产羧酸硫酯的方法，该方法包括在包括至少一种第 2 族金属化合物的催化剂存在下，使下式(I)代表的化合物、羧酸和硫醇发生反应。该生产方法反应操作简单，对环境和人体的负荷小，即使在常温常压下（25℃，1 个大气压）也能催化获得高产率的羧酸硫酯。在式（I）中，R1 和 R2 各自独立地代表具有 1 至 20 个碳原子的烃基。
• Rapid and Convenient Thioester Synthesis Under Phase-Transfer Catalysis Conditions
  作者：Cristian Simion、Iwao Hashimoto、Yoshiharu Mitoma、Alina Marieta Simion、Naoyoshi Egashira

  DOI：10.1080/10426501003713072

  日期：2010.11.23

  Various thioesters were obtained through an efficient phase-transfer catalysis method, by treating several thiophenols with different acyl chlorides, in a biphasic system composed of 10% aqueous NaOH and dichloromethane in the presence of tetrabutylammonium chloride. The thiolation reaction was complete in only 5 minutes, at 0 degrees C.
• A Convenient Method for the Preparation of Thiol Esters
  作者：Tsunco Imamoto、Masahito Kodera、Masataka Yokoyama

  DOI：10.1055/s-1982-29716

  日期：——