Cinnamido benzylpiperidinyl ethoxypropylbenzamide | 1382749-08-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: Cinnamido benzylpiperidinyl ethoxypropylbenzamide
• 英文别名: 2-(4-benzylpiperidin-1-yl)-N-(3-ethoxypropyl)-5-[[(E)-3-phenylprop-2-enoyl]amino]benzamide
• CAS: 1382749-08-7
• 化学式: C₃₃H₃₉N₃O₃
• 分子量: 525.7
• InChiKey: WLBVNLFUCUVTLE-SAPNQHFASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  39
• 可旋转键数：
  12
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  70.7
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• METHOD OF TREATING SKIN WITH microRNA MODULATORS
  申请人：Avon Products, Inc.

  公开号：EP2658537A1

  公开（公告）日：2013-11-06
• Method of Treating Skin with microRNA Modulators
  申请人：Khusial Permanan Raaj

  公开号：US20120165373A1

  公开（公告）日：2012-06-28

  Methods for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ active agents that suppress or down-regulate microRNA expression in dermal fibroblast, resulting in enhanced production of collagen, elastin and/or fibrillin in the skin. Also provided are methods for screening for activity against specific microRNAs and the methods of using active agents identified by the screening protocol in the treatment of skin.
• Modulation of Thymosin Beta-4 in Skin
  申请人：Chen Siming

  公开号：US20130149397A1

  公开（公告）日：2013-06-13

  Methods for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ active agents, other than a retinoid, that stimulate thymosin beta-4 expression in the skin. Also provided are methods for screening for substances which stimulate thymosin beta-4 expression levels and the methods of using active agents identified by the screening protocol in the treatment of skin.
• US8455518B2
  申请人：——

  公开号：US8455518B2

  公开（公告）日：2013-06-04
• US8632827B2
  申请人：——

  公开号：US8632827B2

  公开（公告）日：2014-01-21