1,8-Diazabicyclo<5.3.0>dec-7-en | 7140-57-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂环庚烷
• 英文名称: 1,8-Diazabicyclo<5.3.0>dec-7-en
• 英文别名: 2,5,6,7,8,9-Hexahydro-3H-imidazo[1,2-a]azepine；3,5,6,7,8,9-hexahydro-2H-imidazo[1,2-a]azepine
• CAS: 7140-57-0
• 化学式: C₈H₁₄N₂
• 分子量: 138.213
• InChiKey: ZKNJODFEJANRER-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  15.6
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,8-Diazabicyclo<5.3.0>dec-7-en 、 氢氧化钾 、 甲醇 生成 N-(2-Amonoaethyl)-ε-caprolactam
  参考文献：
  名称：

  HEIDELBERGER C.; GUGGISBERG A.; STEPHANOU E.; HESSE M., HELV. CHIM. ACTA, 1981, 64, NO 2, 399-406

  摘要：

  DOI：
• 作为产物：
  描述：

  N-(2-Amonoaethyl)-ε-caprolactam 、 对甲苯磺酸 生成 1,8-Diazabicyclo<5.3.0>dec-7-en
  参考文献：
  名称：

  HEIDELBERGER C.; GUGGISBERG A.; STEPHANOU E.; HESSE M., HELV. CHIM. ACTA, 1981, 64, NO 2, 399-406

  摘要：

  DOI：

文献信息

• OLIGOCARBONATE MOLECULAR TRANSPORTERS
  申请人：Cooley Christina

  公开号：US20100280219A1

  公开（公告）日：2010-11-04

  A cyclic carbonate monomer, including: wherein R 1 , R 2 , and R 3 are independently selected from the group consisting of H, linear or branched, substituted or unsubstituted alkyl; R 10 is a connecting group selected from the group consisting of linear or branched, substituted or unsubstituted alkyl, heteroalkyl, cycloalkyl, heterocyclic, aryl and heteroaryl; R 4 is an optional bridging group selected from the group consisting of linear or branched, substituted or unsubstituted alkyl, heteroalkyl, cycloalkyl, heterocyclic, aryl and heteroaryl; Z is selected from the group consisting of O, NH, NR, and S; G is a guanidine group; and P is a protecting group. The cylic carbonate monomer can be reacted with an initiator including a drug, drug candidate, probe or other molecule of interest to form an oligomer with the molecule of interest attached to one end of a carbonate backbone and guanidine groups attached to the carbonate backbone.

  一个环状碳酸酯单体，包括：其中R1、R2和R3独立地选择自H、线性或支链、取代或未取代的烷基的组；R10是从线性或支链、取代或未取代的烷基、杂烷基、环烷基、杂环基、芳基和杂芳基中选择的连接基团；R4是可选的桥连基团，选择自线性或支链、取代或未取代的烷基、杂烷基、环烷基、杂环基、芳基和杂芳基的组；Z选择自O、NH、NR和S的组；G是一种鸟嘌呤基团；P是保护基团。环状碳酸酯单体可以与包括药物、药物候选化合物、探针或其他感兴趣分子的引发剂反应，形成一个寡聚体，其中感兴趣分子连接到碳酸酯骨架的一端，鸟嘌呤基团连接到碳酸酯骨架上。
• 5-Substituierte Chinolon- und Naphthyridoncarbonsäure-Derivate
  申请人：BAYER AG

  公开号：EP0284935A1

  公开（公告）日：1988-10-05

  Die Erfindung betrifft 5-substituierte Chinolon-und Naphthyridoncarbonsäure-Derivate der Formel (I) in welcher X, Y, R', R2 und R3 die in der Beschreibung angegebene Bedeutung haben. Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel und Futterzusatzstoffe.

  本发明涉及式(I)的5-取代喹诺酮和萘啶酮羧酸衍生物，其中X，Y，R'，R2和R3具有描述中所述的含义。制备它们的方法以及包含它们的抗菌剂和饲料添加剂。
• Method of Preparing or Synthesizing Polyazamacrocycle Derivatives
  申请人：Cihelnik Simon

  公开号：US20080312430A1

  公开（公告）日：2008-12-18

  The present invention relates to novel processes for the synthesis of polyazamacrocycle derivatives. Furthermore, the present invention relates to novel polyazamacrocycle derivatives as well as novel intermediates for the synthesis of said polyazamacrocycle derivatives.

  本发明涉及一种合成聚氮杂大环衍生物的新工艺。此外，本发明还涉及新的聚氮杂大环衍生物以及用于合成该聚氮杂大环衍生物的新中间体。
• CATALYST COMPOSITION FOR PRODUCTION OF POLYURETHANE RESIN AND METHOD FOR PRODUCING POLYURETHANE RESIN (AS AMENDED)
  申请人：Kometani Hiroyuki

  公开号：US20100130629A1

  公开（公告）日：2010-05-27

  Disclosed is a catalyst composition for polyurethane resin production which contains (A) triethylenediamine, (B) a specific polyisocyanurating catalyst and/or (C) a specific highly temperature-sensitive catalyst. By using this catalyst composition, a polyurethane resin can be molded with good curability, while suppressing initial reactivity. Consequently, a polyurethane resin having excellent moldability and fluidity can be produced with high productivity by using the catalyst composition. The thus-obtained polyurethane resin is suitably applicable to shoe soles. The component (B) is selected from the group consisting of alkali metal salts of carboxylic acids, quaternary ammonium compounds expressed as R 1 R 2 R 3 R 4 N + ,X − , N,N,N′-trimethylaminoethylethanolamine, and 2,4,6-tris(dimethylaminomethyl)phenol, while the component (C) is selected from the group consisting of triazole salts and benzotriazole salts of 1,8-diazabicyclo[5.4.0]undecene-7 or 1,5-diazabicyclo[4.3.0]nonene-5. The mixing ratio of the component (B) and/or the component (C) to the component (A) is from 2% by weight to 60% by weight.

  本发明涉及一种用于聚氨酯树脂生产的催化剂组合物，其包含（A）三乙二胺，（B）特定的聚异氰酸酯催化剂和/或（C）特定的高温敏感催化剂。通过使用这种催化剂组合物，可以制造具有良好可固化性的聚氨酯树脂，同时抑制初始反应性。因此，使用催化剂组合物可以生产具有出色的可塑性和流动性的聚氨酯树脂，并具有高生产率。因此制造的聚氨酯树脂适用于鞋底。组分（B）选自羧酸的碱金属盐、表示为R1R2R3R4N+，X−的季铵化合物、N，N，N′-三甲基氨基乙基乙醇胺和2,4,6-三（二甲胺甲基）苯酚组成的群，而组分（C）选自1,8-二氮杂双环[5.4.0]十一烯-7或1,5-二氮杂双环[4.3.0]壬烯-5的三唑盐和苯并三唑盐组成的群。组分（B）和/或组分（C）与组分（A）的混合比重为2重量％至60重量％。
• Method for the Preparation and Use of Bis (Alkoxysilylorgano)-Dicarboxylates
  申请人：Backer Michael

  公开号：US20130072625A1

  公开（公告）日：2013-03-21

  A method for preparing a bis(alkoxysilylorgano)dicarboxylate includes reacting a haloorganoalkoxysilane, a dimetal salt of a dicarboxyl functional compound, and a phase transfer catalyst. A quaternary iminium compound of a polyaza, polycycloalkene is useful as the phase transfer catalyst. The product may be a bis(alkoxysilylalkyl)fumarate, which is useful as a coupling agent in rubber compositions for tire applications.

  一种制备双（烷氧基硅烷基）二羧酸酯的方法包括反应卤代有机烷氧基硅烷、二羧酸官能化合物的二金属盐和相转移催化剂。一种多氮杂环烷化合物的季铵化合物可用作相转移催化剂。产物可能是双（烷氧基硅烷基）丁烯二酸酯，它可用作轮胎应用的橡胶组合物的偶联剂。