dichloro(trimethylsilylmethyl)silane | 18148-74-8

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: dichloro(trimethylsilylmethyl)silane
• 英文别名: Si',Si'-dichloro-Si,Si,Si-trimethyl-Si,Si'-methanediyl-bis-silane；Si',Si'-Dichlor-Si,Si,Si-trimethyl-Si,Si'-methandiyl-bis-silan；Dichlorsilyl-trimethylsilyl-methan；1,1-Dichloro-3,3-dimethyl-1,3-disilabutane；dichlorosilylmethyl(trimethyl)silane
• CAS: 18148-74-8
• 化学式: C₄H₁₂Cl₂Si₂
• 分子量: 187.216
• InChiKey: LZJINVYTYPELPM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.56
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  dichloro(trimethylsilylmethyl)silane 在 lithium aluminium tetrahydride 作用下， 以 various solvent(s) 为溶剂， 生成 (trimethylsilylmethyl)silane
  参考文献：
  名称：

  Moore, Darren L.; Taylor, Mark P.; Timms, Peter L., Journal of the Chemical Society, Dalton Transactions, 2000, # 16, p. 2673 - 2678

  摘要：

  DOI：
• 作为产物：
  描述：

  magnesium,methanidyl(trimethyl)silane,bromide 在 三氯硅烷 作用下， 生成 dichloro(trimethylsilylmethyl)silane
  参考文献：
  名称：

  Studies in Organosilicon Chemistry. XXXIV. The Reaction of Trimethylsilylmethyl Metallic Compounds with Trichlorosilane

  摘要：

  DOI：

  10.1021/jo01358a008

文献信息

• Dehydrohalogenative coupling reaction of organic halides with silanes
  申请人：Korea Institute of Science and Technology

  公开号：US06251057B1

  公开（公告）日：2001-06-26

  The present invention relates to methods for making the compounds of formula I which is a dehydrohalogenative coupling of hydrochlorosilanes of formula II with organic halides of formula III in the presence of a Lewis base catalyst. R3CH2SiR1Cl2  (I) HSiR1Cl2  (II) R2CH2X  (III) In formulas I and II, R1 represents a hydrogen, chloro, or methyl; in formula III, X represents a chloro or bromo; in formula III, R2 can be selected from the group consisting of a C1-17 alkyl, a C1-10 fluorinated alkyl with partial or full fluorination, a C1-5 alkenyl groups, a silyl group containing alkyls, (CH2)nSiMe3-mClm wherein n is 0 to 2 and m is 0 to 3, aromatic groups, Ar(R′)1 wherein Ar is C6-14 aromatic hydrocarbon, R′ is a C1-4 alkyl, halogen, alkoxy, or vinyl, and q is 0 to 5, a haloalkyl group, (CH2)pX wherein p is 1 to 9 and X is a chloro or bromo; or an aromatic hydrocarbon, Ar CH2X wherein Ar is C6-14 aromatic hydrocarbon and X is a chloro or bromo. in formula I, R3 is the same as R2 in formula III and further, R3 can also be (CH2)pSiR1Cl2 or ArCH2SiR1Cl2 when R2 in formula III is (CH2)pX or ArCH2X, because of the coupling reaction of X with the compound of formula II.

  本发明涉及制备公式I化合物的方法，该方法是在路易斯碱催化剂的存在下，通过公式II的氯硅烷与公式III的有机卤化物的去氢卤素偶联反应得到的。R3CH2SiR1Cl2  (I) HSiR1Cl2  (II) R2CH2X  (III) 在公式I和II中，R1代表氢、氯或甲基；在公式III中，X代表氯或溴；在公式III中，R2可以是以下组中的一种：C1-17烷基、具有部分或完全氟化的C1-10氟化烷基、C1-5烯基、含有烷基的硅基、(CH2)nSiMe3-mClm，其中n为0至2，m为0至3，芳香族基，Ar(R′)1，其中Ar为C6-14芳香族碳氢化合物，R′为C1-4烷基、卤素、烷氧基或乙烯基，q为0至5，卤代烷基，(CH2)pX，其中p为1至9，X为氯或溴；或芳香族碳氢化合物，Ar CH2X，其中Ar为C6-14芳香族碳氢化合物，X为氯或溴。在公式I中，R3与公式III中的R2相同，此外，当公式III中的R2为(CH2)pX或ArCH2X时，由于X与公式II化合物的偶联反应，R3还可以是(CH2)pSiR1Cl2或ArCH2SiR1Cl2。
• Stereochemically nonrigid silanes, germanes, and stannanes. 9. Chiral silylcyclopentadienes and related compounds: mechanistic and stereochemical definition of fluxional behavior
  作者：Alan Bonny、Rupert D. Holmes-Smith、Geoffrey Hunter、Stephen R. Stobart

  DOI：10.1021/ja00371a013

  日期：1982.4
• Synthesis and characterization of mono-, bis-, tris- and tetrakis(trimethylsilylmethyl)silanes: (Me3SiCH2)xSiH4−x (x = 1−4)
  作者：Chris.K. Whitmarsh、Leonard V. Interrante

  DOI：10.1016/0022-328x(91)86347-s

  日期：1991.10

  The mono-, bis-, tris-, and tetrakis(trimethylsilylmethyl)silanes, (Me3SiCH2)(x)SiH4-x (x = 1-4), have been prepared for use as "models" of the various Si-centered functional units in a complex, highly branched polycarbosilane polymer of the approximate composition, "(SiH2CH2)n". These compounds have been characterized by GC, IR, H-1, C-13, Si-29 NMR, MS, and elemental analysis. The IR and NMR data for this series of compounds show distinct trends on increasing substitution, which are related to the structural differences within the series.
• BONNY, A.;HOLMES-SMITH, R. D.;HUNTER, G.;STOBART, S. R., J. AMER. CHEM. SOC., 1982, 104, N 7, 1855-1859
  作者：BONNY, A.、HOLMES-SMITH, R. D.、HUNTER, G.、STOBART, S. R.

  DOI：——

  日期：——
• Moore, Darren L.; Taylor, Mark P.; Timms, Peter L., Journal of the Chemical Society, Dalton Transactions, 2000, # 16, p. 2673 - 2678
  作者：Moore, Darren L.、Taylor, Mark P.、Timms, Peter L.

  DOI：——

  日期：——