3,3-Diisopropyl-1,1,1,5,5,5-hexamethyltrisiloxan | 92810-30-5

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 3,3-Diisopropyl-1,1,1,5,5,5-hexamethyltrisiloxan
• 英文别名: 1,1,1,5,5,5-hexamethyl-3,3-diisopropyltrisiloxane；1,1,1,5,5,5-hexamethyl-3,3-bis(1-methylethyl)trisiloxane；3,3-diisopropyl-1,1,1,5,5,5-hexamethyltrisiloxane；Di(propan-2-yl)-bis(trimethylsilyloxy)silane
• CAS: 92810-30-5
• 化学式: C₁₂H₃₂O₂Si₃
• 分子量: 292.641
• InChiKey: PSCLWXNXYREBTJ-UHFFFAOYSA-N

物化性质

• 沸点：
  250.7±23.0 °C(Predicted)
• 密度：
  0.842±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.95
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  diisopropylsilanediol 、 异丁烯基三甲基硅烷 在 Amberlyst-15 作用下， 以 乙腈 为溶剂， 反应 0.5h， 以87%的产率得到3,3-Diisopropyl-1,1,1,5,5,5-hexamethyltrisiloxan
  参考文献：
  名称：

  O-Metalation of silanols and POSS silanols over Amberlyst-15 catalyst: A facile route to unsymmetrical siloxanes, borasiloxanes and germasiloxanes

  摘要：

  A simple and highly practical Amberlyst-catalyzed direct O-metalation of silanols, POSS silanols and alkoxy-silanes under mild conditions is proposed. This protocol can be applied to the synthesis of a wide range of important organosilicon derivatives such as siloxanes, germasiloxanes, borasiloxanes and functionalized silses-quioxanes. It is worth noting that Amberlyst-15 can be reused for further experiments and its catalytic activity in this process is well-preserved for several recycling steps.

  DOI：

  10.1016/j.ica.2019.03.025

文献信息

• Silylation of Alcohols, Phenols, and Silanols with Alkynylsilanes - an Efficient Route to Silyl Ethers and Unsymmetrical Siloxanes
  作者：Krzysztof Kuciński、Hanna Stachowiak、Grzegorz Hreczycho

  DOI：10.1002/ejoc.202000573

  日期：2020.7.15

  Alkynylsilanes – a missing piece of different silylation agents, can serve as valuable substrates in the O‐silylation through a dealkynative coupling with alcohols or silanols. The described approach displays a whole array of advantages in terms of green chemistry and is a promising alternative to existing methodologies.

  炔基硅烷–缺少的一种不同的甲硅烷基化剂，可以通过与醇或硅烷醇的脱炔基偶联而成为O-硅烷化中的重要底物。所描述的方法在绿色化学方面显示了一系列优势，并且是现有方法的有希望的替代方法。
• A Highly Effective Route to Si−O−Si Moieties through <i>O</i> ‐Silylation of Silanols and Polyhedral Oligomeric Silsesquioxane Silanols with Disilazanes
  作者：Krzysztof Kuciński、Grzegorz Hreczycho

  DOI：10.1002/cssc.201802757

  日期：2019.3.7

  A simple and highly practical catalyst‐free O‐silylation of silanols with commercially available disilazanes has been developed under mild conditions. In the case of polyhedral oligomeric silsesquioxane (POSS) silanols and some other silanols, it was necessary to use catalytic amounts of inexpensive Bi(OTf)3 as additional catalyst. This efficient chlorine‐free protocol involves the synthesis of a wide

  一个简单且高度实用的无催化剂Ø硅醇基与市售二硅氮烷-silylation已经温和的条件下开发的。对于多面体低聚倍半硅氧烷（POSS）硅烷醇和其他一些硅烷醇，必须使用催化量的廉价Bi（OTf）3作为附加催化剂。这种有效的无氯方案涉及多种重要有机硅衍生物的合成，例如不对称二硅氧烷和功能化的倍半硅氧烷。
• Graalmann, Onno; Klingebiel, Uwe; Clegg, William, Chemische Berichte, 1984, vol. 117, # 9, p. 2988 - 2997
  作者：Graalmann, Onno、Klingebiel, Uwe、Clegg, William、Haase, Martin、Sheldrick, George M.

  DOI：——

  日期：——
• GRAALMANN, O.;KLINGEBIEL, U.;CLEGG, W.;HAASE, M.;SHELDRICK, G. M., CHEM. BER., 1984, 117, N 9, 2988-2997
  作者：GRAALMANN, O.、KLINGEBIEL, U.、CLEGG, W.、HAASE, M.、SHELDRICK, G. M.

  DOI：——

  日期：——
• O-Metalation of silanols and POSS silanols over Amberlyst-15 catalyst: A facile route to unsymmetrical siloxanes, borasiloxanes and germasiloxanes
  作者：Krzysztof Kuciński、Grzegorz Hreczycho

  DOI：10.1016/j.ica.2019.03.025

  日期：2019.5

  A simple and highly practical Amberlyst-catalyzed direct O-metalation of silanols, POSS silanols and alkoxy-silanes under mild conditions is proposed. This protocol can be applied to the synthesis of a wide range of important organosilicon derivatives such as siloxanes, germasiloxanes, borasiloxanes and functionalized silses-quioxanes. It is worth noting that Amberlyst-15 can be reused for further experiments and its catalytic activity in this process is well-preserved for several recycling steps.