5-Methyl-N-[5-(4-pyridinyl)-1,3,4-thiadiazol-2-YL]-3-thiophenecarboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: 5-Methyl-N-[5-(4-pyridinyl)-1,3,4-thiadiazol-2-YL]-3-thiophenecarboxamide
• 英文别名: 5-methyl-N-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)thiophene-3-carboxamide
• 化学式: C₁₃H₁₀N₄OS₂
• mdl: MFCD06004883
• 分子量: 302.4
• InChiKey: ZZPDPPLODSJIJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  124
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• [EN] NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME<br/>[FR] NOUVEAUX COMPOSÉS ANTIVIRAUX EFFICACES ET LEURS MÉTHODES D'UTILISATION
  申请人：UNIV PENNSYLVANIA

  公开号：WO2015187827A1

  公开（公告）日：2015-12-10

  The present invention includes compounds that are useful in preventing or treating viral infections caused by an enveloped RNA virus, such as viral infections caused by a filovirus, arenavirus, rhabdovirus, paramyxovirus, orthomyxovirus and/or retrovirus. The present invention further includes compositions comprising such compounds, and methods of treating a viral infection in a subject using such compounds.