2-amino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid 2-methoxy-ethyl ester | 351980-81-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: 2-amino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid 2-methoxy-ethyl ester
• 英文别名: 2-Methoxyethyl 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
• CAS: 351980-81-9
• 化学式: C₁₂H₁₇NO₃S
• mdl: MFCD01335766
• 分子量: 255.338
• InChiKey: UIUDQLUISITCIL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  89.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
  申请人：Carroll William A.

  公开号：US20090018114A1

  公开（公告）日：2009-01-15

  The present application relates to cannabinoid receptor ligands containing compounds of formula (I) wherein A, R 1 , R 2 , and R 3 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

  本申请涉及含有式(I)化合物的大麻素受体配体，其中A、R1、R2和R3如规范中所定义。本申请还涉及包含这种化合物的组合物，以及使用这种化合物和组合物治疗疾病和疾病的方法。
• N-phenyl-4-(4-pyridyl)-2-pyrimidineamine derivatives
  申请人：——

  公开号：US20030236256A1

  公开（公告）日：2003-12-25

  The present invention relates to a method of protecting plants against attack or infestation by phytopathogenic organisms, such as nematodes or especially microorganisms, preferably fungi, bacteria and viruses, or combinations of two or more of these organisms, by applying at least one compound of the formula (I): wherein n is 0 or 1, R 1 is halogen, alkoxy, haloalkyl, haloalkoxy or alkyl, R 2 is hydrogen, halogen, alkyl, haloalkyl, alkoxy or haloalkoxy, each of R 3 , R 4 and R 5 is, independently of the others, hydrogen, lower alkyl or halogen, and R 6 is as defined in claim 1. The invention also relates to new compounds of formula (I), their preparation, use and compositions comprising said compound.

  本发明涉及一种保护植物免受植物病原体，如线虫或特别是微生物，优选为真菌、细菌和病毒，或两种或两种以上这些生物的攻击或感染的方法，通过施用至少一种化合物的公式（I）：其中n为0或1，R1为卤素、烷氧基、卤代烷基、卤代烷氧基或烷基，R2为氢、卤素、烷基、卤代烷基、烷氧基或卤代烷氧基，R3、R4和R5中的每一个独立地为氢、较低烷基或卤素，R6如权利要求1所定义。本发明还涉及公式（I）的新化合物、其制备、使用以及包含所述化合物的组合物。
• Benzamidoacetonitriles and their use as antiparastics
  申请人：——

  公开号：US20040220055A1

  公开（公告）日：2004-11-04

  The invention relates to compounds of the general formula 1 and optionally the enantiomers thereof. These compounds have advantageous pesticidal properties. They are especially suitable for controlling parasites in warm-blooded animals.

  本发明涉及一般式1的化合物及其对昆虫的杀虫性质，其中还包括它们的对映体。这些化合物在温血动物中控制寄生虫方面特别有效。
• Organic compounds
  申请人：——

  公开号：US20040242913A1

  公开（公告）日：2004-12-02

  The invention relates to compounds of the general formula (I) 1 wherein Ar 1 , Ar 2 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , W, X, a, b and c have the significances given in the specification, and optionally the enantiomers thereof. The active ingredients have advantageous pesticidal properties. They are especially suitable for controlling parasites on warm-blooded animals.

  本发明涉及一般式（I）的化合物，其中Ar1，Ar2，R4，R5，R6，R7，R8，R9，R10，W，X，a，b和c具有规范中给定的含义，以及它们的对映体。这些活性成分具有有利的杀虫性能。它们特别适用于控制温血动物上的寄生虫。
• Organic Compounds
  申请人：Bollinger Pietro

  公开号：US20090131408A1

  公开（公告）日：2009-05-21

  The present invention relates to novel aza-thia-benzoazulene derivatives of formula I as defined in the claims, their preparation, the use of these novel compounds for the preparation of pharmaceutical compositions, the use of these novel compounds and compositions for managing arthritis and arthritis-related conditions as well as in the treatment of pain in animals and humans. More particularly, the present invention relates to pharmaceutical, preferably veterinary compositions and methods for reducing inflammation and pain associated with acute inflammation of body parts, particularly joints, due to injury or due to arthritic conditions or other disease conditions.

  本发明涉及一种新型的aza-thia-benzoazulene衍生物，其化学式如权利要求中所定义，其制备方法，使用这些新型化合物制备药物组合物的方法，使用这些新型化合物和组合物治疗关节炎和与关节炎相关的疾病以及治疗动物和人体疼痛。更具体地说，本发明涉及制备药物，优选为兽医用药物组成物，以及减少由于损伤或由于关节炎或其他疾病状况导致的身体部位，特别是关节的急性炎症和疼痛的方法。