4,7-bis(5-bromothiophen-2-yl)-5,6-dinitro-2H-[1,2,5]thiadiazolo[2,3-a]pyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: 4,7-bis(5-bromothiophen-2-yl)-5,6-dinitro-2H-[1,2,5]thiadiazolo[2,3-a]pyridine
• 化学式: C14H6Br2N4O4S3
• 分子量: 550.2
• InChiKey: PRXGOPPKCWEVCO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  27
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  189
• 氢给体数：
  1
• 氢受体数：
  9

文献信息

• Highly Emissive Far-Red/Near-Infrared Fluorescent Conjugated Polymer-Based Nanoparticles
  申请人：National University of Singapore

  公开号：US20150175747A1

  公开（公告）日：2015-06-25

  A series of conjugated polymer-based nanoparticles having far-red/near infrared emission ranges are disclosed. Cross coupling methods to prepare the conjugated polymers and methods of nanoparticle preparation are also discussed. The conjugated polymer nanoparticles are used as FR/NIR fluorescent probes in in vitro and in vivo biosensing and bioimaging applications, and are also used in photoacoustic imaging as contrast agents. Finally, use of the conjugated polymer nanoparticles in photothermal therapy is described.

  本发明公开了一系列基于共轭聚合物的纳米颗粒，具有远红外/近红外发射范围。同时，还讨论了制备共轭聚合物的交叉偶联方法和纳米颗粒制备方法。这些共轭聚合物纳米颗粒可用作体外和体内生物传感和生物成像应用中的远红外/近红外荧光探针，也可用作光声成像对比剂。最后，还描述了在光热疗法中使用共轭聚合物纳米颗粒的方法。
• [EN] HIGHLY EMISSIVE FAR-RED/NEAR-INFRARED FLUORESCENT CONJUGATED POLYMER-BASED NANOPARTICLES<br/>[FR] NANOPARTICULES À BASE DE POLYMÈRE CONJUGUÉ FLUORESCENT À ÉMISSION ÉLEVÉE DANS LE ROUGE LOINTAIN/INFRAROUGE PROCHE
  申请人：UNIV SINGAPORE

  公开号：WO2014017983A1

  公开（公告）日：2014-01-30

  A series of conjugated polymer-based nanoparticles having far-red/near infrared emission ranges are disclosed. Cross coupling methods to prepare the conjugated polymers and methods of nanoparticle preparation are also discussed. The conjugated polymer nanoparticles are used as FR/NIR fluorescent probes in in vitro and in vivo biosensing and bioimaging applications, and are also used in photoacoustic imaging as contrast agents. Finally, use of the conjugated polymer nanoparticles in photothermal therapy is described.