4-(2,4-dichlorophenoxy)-1-[(3S)-3-methylpiperidin-1-yl]butan-1-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 4-(2,4-dichlorophenoxy)-1-[(3S)-3-methylpiperidin-1-yl]butan-1-one
• 化学式: C₁₆H₂₁Cl₂NO₂
• 分子量: 330.2
• InChiKey: KTIVGPVAPGTPPW-LBPRGKRZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION<br/>[FR] COMPOSÉS ET PROCÉDÉS FAVORISANT LA DIFFÉRENCIATION DE PRÉCURSEURS D'OLIGODENDROCYTES
  申请人：CLEVELAND CLINIC FOUND

  公开号：WO2022006518A1

  公开（公告）日：2022-01-06

  A method of promoting the differentiation of an oligodendrocyte precursor cell is disclosed herein. The method includes administering to the oligodendrocyte precursor cell an effective amount of a compound capable of promoting oligodendrocyte precursor cell differentiation. Also disclosed herein is a method of treating a neurodegenerative disorder, including a demyelinating disease such as multiple sclerosis, in a subject in need thereof, comprising administering to the subject a compound disclosed herein.