[Dimethylamino-(3-methyltriazolo[4,5-b]pyridin-3-ium-1-yl)methylidene]-dimethylazanium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三唑并吡啶类
• 英文名称: [Dimethylamino-(3-methyltriazolo[4,5-b]pyridin-3-ium-1-yl)methylidene]-dimethylazanium
• 英文别名: [dimethylamino-(3-methyltriazolo[4,5-b]pyridin-3-ium-1-yl)methylidene]-dimethylazanium
• 化学式: C11H18N6+2
• 分子量: 234.3
• InChiKey: WBHUSRNQCPPZBJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  40.8
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• PROGRAMMABLE SELF-ASSEMBLED NANOSTRUCTURES BASED ON SIDECHAIN-MODIFIED PNA FOR THE MULTIVALENT DISPLAY OF LIGANDS
  申请人：Appella Daniel H.

  公开号：US20140148500A1

  公开（公告）日：2014-05-29

  The invention concerns compositions comprising strands of polynucleotide and strands of PNA, each PNA strand comprising: (i) from 2 to 50 nucleobase subunits and (ii) one or more gamma substituents. The PNA strands are complementary to at least a portion of at least some of the polynucleotide strands, and the molar ratio of PNA strands to polynucleotide strands being at least 1:1. Certain gamma substituents are capable of effecting attachment of a PNA strand to a cell. The invention also concerns construction of nanostructure platforms and vaccines and use of the inventive compositions in inhibiting disease states in mammals.
• cGAP-PNA MULTIVALENT PEPTIDE NUCLEIC ACID LIGAND DISPLAY
  申请人：THE USA, AS REPRESENTED BY THE SECRETARY, DEPART- MENT OF HEALTH AND HUMAN SERVICES

  公开号：US20170002355A1

  公开（公告）日：2017-01-05

  Described herein are compositions composed of peptide nucleic acid strands. In some aspects the peptide nucleic acid strands are complementary to at least a portion of another peptide nucleic acid strand that may have one or more gamma substituents, where the ratio of PNA strands is least 1:1. Certain gamma substituents are capable of effecting attachment of a PNA strand to a cell. The disclosure also concerns construction of nanostructure platforms and vaccines and use of the inventive compositions in inhibiting disease states in mammals.