3-(4-ethoxyphenyl)-N-[(4-ethylphenyl)methyl]-1,2-dihydrotriazolo[4,5-b]pyridin-6-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三唑并吡啶类
• 英文名称: 3-(4-ethoxyphenyl)-N-[(4-ethylphenyl)methyl]-1,2-dihydrotriazolo[4,5-b]pyridin-6-amine
• 化学式: C₂₂H₂₅N₅O
• 分子量: 375.5
• InChiKey: DIMDGJFHTGFEKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  61.4
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVIRUS INFECTION
  申请人：Siga Technologies Inc.

  公开号：US20140243367A1

  公开（公告）日：2014-08-28

  Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever.
• US8754082B2
  申请人：——

  公开号：US8754082B2

  公开（公告）日：2014-06-17
• US9096597B2
  申请人：——

  公开号：US9096597B2

  公开（公告）日：2015-08-04