3-(4-Hydroxy-1-methylpiperidin-1-ium-3-yl)propanoate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 3-(4-Hydroxy-1-methylpiperidin-1-ium-3-yl)propanoate
• 英文别名: 3-(4-hydroxy-1-methylpiperidin-1-ium-3-yl)propanoate
• 化学式: C9H17NO3
• 分子量: 187.24
• InChiKey: QRGOWSRFRLTTNK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  64.8
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• FORMULATIONS AND METHODS FOR STABILIZING PCR REAGENTS
  申请人：BIOMATRICA, INC.

  公开号：US20150329849A1

  公开（公告）日：2015-11-19

  Described herein are stabilized polymerase compositions comprising a polymerase and an polymerase stabilizing agent, such as a non-detergent zwitterionic stabilizer or a cationic ester disclosed, for use in nucleic acid amplification or nucleic acid sequencing. Compositions are provided for the stabilization of one or more polymerases in a single stabilized liquid formulation. Also disclosed are methods for making and using stabilized polymerase compositions and kits for nucleic acid amplification and sequencing comprising the stabilized polymerase compositions provided.

  本文描述了稳定的聚合酶组合物，包括聚合酶和聚合酶稳定剂，例如非离子洗涤剂双性稳定剂或阳离子酯类稳定剂，用于核酸扩增或核酸测序。提供了用于单个稳定液体配方中稳定一个或多个聚合酶的组合物。还公开了制备和使用稳定聚合酶组合物的方法以及包含所提供的稳定聚合酶组合物的核酸扩增和测序试剂盒。
• US9725703B2
  申请人：——

  公开号：US9725703B2

  公开（公告）日：2017-08-08
• [EN] FORMULATIONS AND METHODS FOR STABILIZING PCR REAGENTS<br/>[FR] FORMULATIONS ET PROCÉDÉS POUR STABILISER DES RÉACTIFS PCR
  申请人：BIOMATRICA INC

  公开号：WO2014100755A2

  公开（公告）日：2014-06-26

  Described herein are stabilized polymerase compositions comprising a polymerase and an polymerase stabilizing agent, such as a non-detergent zwitterionic stabilizer or a cationic ester disclosed, for use in nucleic acid amplification or nucleic acid sequencing. Compositions are provided for the stabilization of one or more polymerases in a single stabilized liquid formulation. Also disclosed are methods for making and using stabilized polymerase compositions and kits for nucleic acid amplification and sequencing comprising the stabilized polymerase compositions provided.