1-isothiocyanato-4-methylsulfinylbutane

• 分子结构分类: 有机化合物 - 有机硫化合物 - 亚砜
• 英文名称: 1-isothiocyanato-4-methylsulfinylbutane
• 化学式: C12H22N2O2S4
• 分子量: 354.6
• InChiKey: UEKJGWMAHPEGHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  20
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  162
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• [EN] METHOD OF TREATING HAIR AGEING<br/>[FR] MÉTHODE DE TRAITEMENT DU VIEILLISSEMENT CAPILLAIRE
  申请人：UNILEVER PLC

  公开号：WO2014095289A2

  公开（公告）日：2014-06-26

  Hair ageing is a major age-related consumer issue (hair loss, thinning hair, loss of shine, increased number of grey hairs, etc). Biological routes for hair growth or preventing hair greying provide effective opportunities to target consumer hair issues. Currently, Minoxidil ™ and Finasteride™ are the only clinically proven, mildly effective products available for hair growth and both are classified as medicines and therefore not suitable for cosmetic use. The identification of cosmetic ingredients which are able to boost hair growth, maintain anagen and/or prevent catagen may prove to be effective anti ageing treatments to prevent or attenuate some of the symptoms associated with hair ageing. This invention relates to a method of treating hair ageing. In particular the method relates to treating hair ageing through application to hair fibres of a composition comprising a nuclear factor erythroid-2 related factor 2 (also known as NFE2L2or Nrf2) agonist.