4-[2-[2-methyl-5-[(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carbonyl]thiophen-3-yl]cyclopenten-1-yl]thiophene-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: 4-[2-[2-methyl-5-[(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carbonyl]thiophen-3-yl]cyclopenten-1-yl]thiophene-2-carboxylic acid
• 化学式: C₂₅H₂₉NO₅S₂
• 分子量: 487.6
• InChiKey: AEQQKGHJDXLZKB-IBGZPJMESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  33
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  140
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• [EN] PEPTIDOMIMETICS POSSESSING PHOTO-CONTROLLED BIOLOGICAL ACTIVITY<br/>[FR] PEPTIDOMIMÉTIQUES DONT L'ACTIVITÉ BIOLOGIQUE EST COMMANDÉE PAR LA LUMIÈRE
  申请人：KARLSRUHER INST FÜR TECHNOLOGIE

  公开号：WO2014127919A1

  公开（公告）日：2014-08-28

  The present invention relates to pharmaceutically and/or diagnostically active compounds, in particular peptide analogues (peptidomimetics), which can be reversibly controlled between an active and an inactive state by irradiation with light of different wavelengths. The present invention further relates to an intermediate compound usable in the manufacture of such pharmaceutically and/or diagnostically active compounds, as well as a manufacturing method thereof.