5-Methyl-4-[2-[2-methyl-5-[2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl]thiophen-3-yl]cyclopenten-1-yl]thiophene-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: 5-Methyl-4-[2-[2-methyl-5-[2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl]thiophen-3-yl]cyclopenten-1-yl]thiophene-2-carboxylic acid
• 英文别名: 5-methyl-4-[2-[2-methyl-5-[2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl]thiophen-3-yl]cyclopenten-1-yl]thiophene-2-carboxylic acid
• 化学式: C₂₄H₂₉NO₅S₂
• 分子量: 475.6
• InChiKey: JNVYTYYFQDIEAZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  32
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  140
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• PEPTIDOMIMETICS POSSESSING PHOTO-CONTROLLED BIOLOGICAL ACTIVITY
  申请人：KARLSRUHER INSTITUT FÜR TECHNOLOGIE

  公开号：US20170051017A1

  公开（公告）日：2017-02-23

  The present invention relates to pharmaceutically and/or diagnostically active compounds, in particular peptide analogues (peptidomimetics), which can be reversibly controlled between an active and an inactive state by irradiation with light of different wavelengths. The present invention further relates to an intermediate compound usable in the manufacture of such pharmaceutically and/or diagnostically active compounds, as well as a manufacturing method thereof.

  本发明涉及药理学和/或诊断上有活性的化合物，特别是肽类似物（肽模拟物），这些化合物可以通过不同波长的光照在活性状态和非活性状态之间进行可逆控制。本发明还涉及一种可用于制造此类药理学和/或诊断上有活性的化合物的中间体化合物，以及其制造方法。
• US9481712B2
  申请人：——

  公开号：US9481712B2

  公开（公告）日：2016-11-01
• [EN] PEPTIDOMIMETICS POSSESSING PHOTO-CONTROLLED BIOLOGICAL ACTIVITY<br/>[FR] PEPTIDOMIMÉTIQUES DONT L'ACTIVITÉ BIOLOGIQUE EST COMMANDÉE PAR LA LUMIÈRE
  申请人：KARLSRUHER INST FÜR TECHNOLOGIE

  公开号：WO2014127919A1

  公开（公告）日：2014-08-28

  The present invention relates to pharmaceutically and/or diagnostically active compounds, in particular peptide analogues (peptidomimetics), which can be reversibly controlled between an active and an inactive state by irradiation with light of different wavelengths. The present invention further relates to an intermediate compound usable in the manufacture of such pharmaceutically and/or diagnostically active compounds, as well as a manufacturing method thereof.