1-(2-Tert-butyl-2,7-diazaspiro[3.5]nonan-7-yl)ethanone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-(2-Tert-butyl-2,7-diazaspiro[3.5]nonan-7-yl)ethanone
• 英文别名: 1-(2-tert-butyl-2,7-diazaspiro[3.5]nonan-7-yl)ethanone
• 化学式: C₁₃H₂₄N₂O
• 分子量: 224.34
• InChiKey: FIUDYWQWASSTCG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  23.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• 1,3-DIARYL-SUBSTITUTED HETEROCYCLIC PESTICIDES
  申请人：E I DU PONT DE NEMOURS AND COMPANY

  公开号：US20140249025A1

  公开（公告）日：2014-09-04

  Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein Q is and Z 1 , Z 2 , J 1 , J 2 , M, R 1a , R 1b , R 2a , R 2b , R 2c , R 2d and R 14 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.
• CARM1 INHIBITORS AND USES THEREOF
  申请人：Epizyme, Inc.

  公开号：US20170305922A1

  公开（公告）日：2017-10-26

  Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein R1, R2a, R2b, R3 and Ring B are as defined herein, and Ring A is a group of Formula (A-i), (A-ii), or (A-iii): wherein R, R, R, R, and R are as defined herein. Compounds of the present invention are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described.
• PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME
  申请人：Abide Therapeutics, Inc.

  公开号：US20190256494A1

  公开（公告）日：2019-08-22

  Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of, for example, pain.
• METHODS OF TREATING DISEASE WITH MAGL INHIBITORS
  申请人：H. Lundbeck A/S

  公开号：US20220110933A1

  公开（公告）日：2022-04-14

  Provided herein are methods for the treatment of disease with monoacylglycerol lipase (MAGL) inhibitors.
• US9113631B2
  申请人：——

  公开号：US9113631B2

  公开（公告）日：2015-08-25