3-(Dimethylamino)-1-propan-2-ylpiperidin-4-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 3-(Dimethylamino)-1-propan-2-ylpiperidin-4-ol
• 英文别名: 3-(dimethylamino)-1-propan-2-ylpiperidin-4-ol
• 化学式: C₁₀H₂₂N₂O
• 分子量: 186.29
• InChiKey: OBKGVVOWEAVIID-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26.7
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Antiproliferative pyrimidine-based compounds
  申请人：G1 Therapeutics, Inc.

  公开号：US10654831B2

  公开（公告）日：2020-05-19

  This invention is in the area of pyrimidine-based compounds for the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.

  本发明属于嘧啶类化合物领域，用于治疗涉及细胞异常增殖的疾病，包括但不限于肿瘤和癌症。
• ANTIPROLIFERATIVE PYRIMIDINE-BASED COMPOUNDS
  申请人：G1 Therapeutics, Inc.

  公开号：US20190135784A1

  公开（公告）日：2019-05-09

  This invention is in the area of pyrimidine-based compounds for the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
• PYRIMIDINE-BASED ANTIPROLIFERATIVE AGENTS
  申请人：G1 Therapeutics, Inc.

  公开号：US20210047328A1

  公开（公告）日：2021-02-18

  This invention is in the area of pyrimidine-based compounds for the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.
• US8829012B2
  申请人：——

  公开号：US8829012B2

  公开（公告）日：2014-09-09