1-[4-(2-Methoxyethyl)piperidin-1-yl]pentan-1-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-[4-(2-Methoxyethyl)piperidin-1-yl]pentan-1-one
• 英文别名: 1-[4-(2-methoxyethyl)piperidin-1-yl]pentan-1-one
• 化学式: C₁₃H₂₅NO₂
• 分子量: 227.34
• InChiKey: NZXFQDCZAKJSQE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• US20140274903A1
  申请人：——

  公开号：US20140274903A1

  公开（公告）日：2014-09-18
• TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES
  申请人：NOVO NORDISK HEALTHCARE AG

  公开号：US20160355859A1

  公开（公告）日：2016-12-08

  Methods for conjugating peptides are provided comprising i) reacting a peptide with a first compound comprising a functional group in the presence of a transglutaminase capable of incorporating said compound into the peptide to form a transaminated peptide, and ii) reacting said transaminated peptide with e.g. a functionalized polymer capable of reacting with the functional group incorporated in the peptide in the enzymatic reaction.