1-(2-Ethylpiperidin-1-yl)butan-1-one | 57150-37-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-(2-Ethylpiperidin-1-yl)butan-1-one
• CAS: 57150-37-5
• 化学式: C₁₁H₂₁NO
• mdl: MFCD01340161
• 分子量: 183.29
• InChiKey: IHCUOSILMQTAFN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.909
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Peptidomimetic proteasome inhibitors
  申请人：CORNELL UNIVERSITY

  公开号：US11203613B2

  公开（公告）日：2021-12-21

  The compounds of the present invention are represented by the following compounds having Formula (I) and Formula (I′): where the substituents R, R1, R3 R4, R′, W, X, Y, Z, k, and m are as defined herein and where the substituents R, R1, R2, R3, R4, X, Y, Z, and m are as defined herein. These compounds are used in the treatment of bacterial infections, parasite infections, fungal infections, cancer, immunologic disorders, autoimmune disorders, neurodegenerative diseases and disorders, inflammatory disorders, or muscular dystrophy or for providing immunosuppression for transplanted organs or tissues.

  本发明的化合物由具有式（I）和式（I′）的下列化合物表示：其中取代基R、R1、R3 R4、R′、W、X、Y、Z、k和m如本文所定义，取代基R、R1、R2、R3、R4、X、Y、Z和m如本文所定义。这些化合物可用于治疗细菌感染、寄生虫感染、真菌感染、癌症、免疫性疾病、自身免疫性疾病、神经退行性疾病、炎症性疾病或肌肉萎缩症，或为移植器官或组织提供免疫抑制。
• PEPTIDOMIMETIC PROTEASOME INHIBITORS
  申请人：CORNELL UNIVERSITY

  公开号：US20200317729A1

  公开（公告）日：2020-10-08

  The compounds of the present invention are represented by the following compounds having Formula (I) and Formula (I′): where the substituents R, R 1 , R 3 R 4 , R′, W, X, Y, Z, k, and m are as defined herein and where the substituents R, R 1 , R 2 , R 3 , R 4 , X, Y, Z, and m are as defined herein. These compounds are used in the treatment of bacterial infections, parasite infections, fungal infections, cancer, immunologic disorders, autoimmune disorders, neurodegenerative diseases and disorders, inflammatory disorders, or muscular dystrophy or for providing immunosuppression for transplanted organs or tissues.
• US7365093B2
  申请人：——

  公开号：US7365093B2

  公开（公告）日：2008-04-29