1,2-bis(4-amino 6-methoxy-1,3,5-triazin-2-yl)diazene | 1033125-79-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 1,2-bis(4-amino 6-methoxy-1,3,5-triazin-2-yl)diazene
• 英文别名: 4-[(4-Amino-6-methoxy-1,3,5-triazin-2-yl)diazenyl]-6-methoxy-1,3,5-triazin-2-amine；4-[(4-amino-6-methoxy-1,3,5-triazin-2-yl)diazenyl]-6-methoxy-1,3,5-triazin-2-amine
• CAS: 1033125-79-9
• 化学式: C₈H₁₀N₁₀O₂
• 分子量: 278.233
• InChiKey: AOABWZGQPCBENM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  173
• 氢给体数：
  2
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  1,2-bis(4-amino 6-methoxy-1,3,5-triazin-2-yl)diazene 在 一水合肼 作用下， 以 乙腈 为溶剂， 反应 2.0h， 以94%的产率得到N,N'-bis(4-amino-6-methoxy-1,3,5-triazin-2-yl)hydrazine
  参考文献：
  名称：

  Azo bond hydrogenation with hydrazine, R–NHNH2, and hydrazobenzene

  摘要：

  Hydrogenation of azo bonds with hydrazine, mono-substituted hydrazine, and hydrazobenzene was studied with selected diazene compounds under oxygen-free conditions. The reactions proceed rapidly and in high yield in several solvents, utilizing all N-H protons. While the reduction process is accompanied by the evolution of nitrogen gas in the case of N(2)H(4), the intermediacy of diimide could not be confirmed by standard trapping experiments. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.03.083
• 作为产物：
  描述：

  N,N'-bis(4-amino-6-methoxy-1,3,5-triazin-2-yl)hydrazine 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 乙腈 为溶剂， 反应 4.0h， 以94%的产率得到1,2-bis(4-amino 6-methoxy-1,3,5-triazin-2-yl)diazene
  参考文献：
  名称：

  Azo bond hydrogenation with hydrazine, R–NHNH2, and hydrazobenzene

  摘要：

  Hydrogenation of azo bonds with hydrazine, mono-substituted hydrazine, and hydrazobenzene was studied with selected diazene compounds under oxygen-free conditions. The reactions proceed rapidly and in high yield in several solvents, utilizing all N-H protons. While the reduction process is accompanied by the evolution of nitrogen gas in the case of N(2)H(4), the intermediacy of diimide could not be confirmed by standard trapping experiments. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.03.083