4-Piperidin-4-ylbenzo[de]isoquinoline-1,3-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 4-Piperidin-4-ylbenzo[de]isoquinoline-1,3-dione
• 英文别名: 4-piperidin-4-ylbenzo[de]isoquinoline-1,3-dione
• 化学式: C₁₇H₁₆N₂O₂
• 分子量: 280.32
• InChiKey: VFHUBOBJYUMBBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• WATER-SOLUBLE PEPTIDE FLUORESCENCE MATERIAL
  申请人：NATIONAL CHIAO TUNG UNIVERSITY

  公开号：US20180052170A1

  公开（公告）日：2018-02-22

  A water-soluble peptide fluorescence material having a structure of formula (I): In formula (I), n is an integer greater than or equal to 1, R 1 is independently selected from hydrogen or a nitrogen-containing functional group, R 2 is independently selected from hydrogen or alkyl, and A 1 is polymerized by at least one amino acid monomer and having a structure of formula (II): In formula (II), m is an integer greater than or equal to 1, and R 3 in each, of the amino acid monomers of A 1 is independently selected from hydrogen, alkyl, aralkyl, alkylthioaalkyl, hydroxyaralky, heteroaralkyl, carboxylalkyl, or guanidinylalkyl, A 2 is —OR 5 or —N(R 4 ) 2 , and R 4 is independently selected from hydrogen, alkyl, aralkyl, alkylthioaalkyl, hydroxyaralky, heteroaralkyl, carboxylalkyl, guanidinylalkyl, monoglycosyl, biglycosyl, or oligosaccharyl, and R 5 is hydrogen, alkyl, aralkyl, alkylthioaalkyl, hydroxyaralky, heteroaralkyl, carboxylalkyl, or guanidinylalkyl.

  具有以下结构的水溶性肽荧光材料（I）： 在式（I）中，n是大于或等于1的整数，R1独立选择自氢或含氮功能基团，R2独立选择自氢或烷基，A1由至少一种氨基酸单体聚合而成，具有以下结构（II）： 在式（II）中，m是大于或等于1的整数，A1的氨基酸单体中的每一个R3独立选择自氢、烷基、芳基烷基、烷硫基烷基、羟基芳基、杂环芳基、羧基烷基或胍基烷基，A2为—OR5或—N(R4)2，R4独立选择自氢、烷基、芳基烷基、烷硫基烷基、羟基芳基、杂环芳基、羧基烷基、胍基烷基、单糖基、双糖基或寡糖基，R5为氢、烷基、芳基烷基、烷硫基烷基、羟基芳基、杂环芳基、羧基烷基或胍基烷基。
• Water-soluble peptide fluorescence material
  申请人：NATIONAL CHIAO TUNG UNIVERSITY

  公开号：US10222381B2

  公开（公告）日：2019-03-05

  A water-soluble peptide fluorescence material having a structure of formula (I): In formula (I), n is an integer greater than or equal to 1, R1 is independently selected from hydrogen or a nitrogen-containing functional group, R2 is independently selected from hydrogen or alkyl, and A1 is polymerized by at least one amino acid monomer and having a structure of formula (II): In formula (II), m is an integer greater than or equal to 1, and R3 in each, of the amino acid monomers of A1 is independently selected from hydrogen, alkyl, aralkyl, alkylthioaalkyl, hydroxyaralky, heteroaralkyl, carboxylalkyl, or guanidinylalkyl, A2 is —OR5 or —N(R4)2, and R4 is independently selected from hydrogen, alkyl, aralkyl, alkylthioaalkyl, hydroxyaralky, heteroaralkyl, carboxylalkyl, guanidinylalkyl, monoglycosyl, biglycosyl, or oligosaccharyl, and R5 is hydrogen, alkyl, aralkyl, alkylthioaalkyl, hydroxyaralky, heteroaralkyl, carboxylalkyl, or guanidinylalkyl.

  一种具有式 (I) 结构的水溶性多肽荧光材料： 式（I）中，n 是大于或等于 1 的整数，R1 独立选自氢或含氮官能团，R2 独立选自氢或烷基，A1 由至少一种氨基酸单体聚合而成，具有式（II）结构： 在式 (II) 中，m 是大于或等于 1 的整数，A1 的每种氨基酸单体中的 R3 独立选自氢、烷基、芳基、烷硫基、羟基芳基、杂芳基、羧基或胍基烷基，A2 是-OR5 或-N(R4)2、和 R4 独立选自氢、烷基、芳基、烷硫基、羟基芳基、杂芳基、羧基芳基、胍基芳基、单甘露糖基、双甘露糖基或低聚糖基，和 R5 是氢、烷基、芳基、烷硫基、羟基芳基、杂芳基、羧基芳基或胍基芳基。