5-Hexyl-2,1,3-benzoxadiazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶二唑类
• 英文名称: 5-Hexyl-2,1,3-benzoxadiazole
• 英文别名: 5-hexyl-2,1,3-benzoxadiazole
• 化学式: C₁₂H₁₆N₂O
• 分子量: 204.27
• InChiKey: YUYNQPOZBWRRIW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  38.9
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Antibacterial compounds
  申请人：Redx Pharma PLC

  公开号：US10385065B2

  公开（公告）日：2019-08-20

  The invention relates to antibacterial and anti-mycobacterial drug compounds of formula I. It also relates to pharmaceutical formulations of antibacterial drug compounds. It also relates to uses of the derivatives in treating bacterial infections, and methods of treating bacterial infections. The invention is also directed to antibacterial drug compounds capable of treating bacterial infections that are currently hard to treat with existing drug compounds, e.g., those caused by resistant bacterial or mycobacterial strains.

  本发明涉及式 I 的抗菌和抗霉菌药物化合物，还涉及抗菌药物化合物的药物制剂。 本发明还涉及这些衍生物在治疗细菌感染中的用途，以及治疗细菌感染的方法。 本发明还涉及能够治疗目前难以用现有药物化合物治疗的细菌感染的抗菌药物化合物，例如由抗药性细菌或分枝杆菌菌株引起的细菌感染。
• ANTIBACTERIAL COMPOUNDS
  申请人：REDX PHARMA PLC

  公开号：US20170158708A1

  公开（公告）日：2017-06-08

  The invention relates to antibacterial and anti-mycobacterial drug compounds of formula I. It also relates to pharmaceutical formulations of antibacterial drug compounds. It also relates to uses of the derivatives in treating bacterial infections, and methods of treating bacterial infections. The invention is also directed to antibacterial drug compounds capable of treating bacterial infections that are currently hard to treat with existing drug compounds, e.g., those caused by resistant bacterial or mycobacterial strains.