Methyl 2-amino-4-(4-cyclohexylphenyl)-5-methylthiophene-3-carboxylate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: Methyl 2-amino-4-(4-cyclohexylphenyl)-5-methylthiophene-3-carboxylate
• 化学式: C₁₉H₂₃NO₂S
• mdl: MFCD01924193
• 分子量: 329.5
• InChiKey: JEELCXOZKKIIHR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  80.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] ANTIBACTERIAL DRUG FOR TREATMENT OF STAPHYLOCOCCUS AUREUS AND OTHER GRAM-POSITIVE BACTERIAL INFECTIONS<br/>[FR] MÉDICAMENT ANTIBACTÉRIEN POUR LE TRAITEMENT D'INFECTIONS À STAPHYLOCOCCUS AUREUS ET D'AUTRES BACTÉRIES GRAM POSITIF
  申请人：SIGA TECHNOLOGIES INC

  公开号：WO2009124086A2

  公开（公告）日：2009-10-08

  Compounds, methods and pharmaceutical compositions for treating bacterial infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of bacterial infections such as caused by the Staphylococcus aureus family is disclosed.