9-Methyl-3-oxa-7-azabicyclo[3.3.1]nonane

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 9-Methyl-3-oxa-7-azabicyclo[3.3.1]nonane
• 英文别名: 9-methyl-3-oxa-7-azabicyclo[3.3.1]nonane
• 化学式: C₈H₁₅NO
• 分子量: 141.21
• InChiKey: HYFGAVWSXVIGKN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  21.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF
  申请人：Xuanzhu Pharma Co., Ltd.

  公开号：EP2612860B1

  公开（公告）日：2017-03-15
• [EN] SUBSTITUTED PHENYL-1H-PYRROLO [2, 3-c] PYRIDINE DERIVATIVES<br/>[FR] DÉRIVÉS DE PHÉNYL-1H-PYRROLO [2, 3-C] PYRIDINE SUBSTITUÉS
  申请人：[en]JANSSEN PHARMACEUTICA NV

  公开号：WO2022253167A1

  公开（公告）日：2022-12-08

  The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, including but not limited to leukemia, myelodysplastic syndrome (MDS), and myeloproliferative neoplasms (MPN); and diabetes.