3-(4-Methoxyphenyl)-5-[(5-nitrothiophen-2-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: 3-(4-Methoxyphenyl)-5-[(5-nitrothiophen-2-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
• 化学式: C15H10N2O4S3
• mdl: MFCD01836919
• 分子量: 378.5
• InChiKey: SPYIETQLOVDJCF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  161
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• THIOL ISOMERASES INHIBITORS FOR THE TREATMENT AND PREVENTION OF FOOD ALLERGIES, ALLERGIC DISEASES, AND INFLAMMATORY DISEASES
  申请人：WESTERN NEW ENGLAND UNIVERSITY

  公开号：US20210128679A1

  公开（公告）日：2021-05-06

  Disclosed are methods of treating, inhibiting, or preventing the development of, a food allergy in a patient by administering a therapeutically effective amount of a thiol isomerase inhibitor to a patient in need thereof. Also disclosed are methods for treatment of other allergic diseases and inflammatory diseases.
• [EN] THIOL ISOMERASES INHIBITORS FOR THE TREATMENT AND PREVENTION OF FOOD ALLERGIES, ALLERGIC DISEASES, AND INFLAMMATORY DISEASES<br/>[FR] INHIBITEURS DE THIOL ISOMÉRASES POUR LE TRAITEMENT ET LA PRÉVENTION D'ALLERGIES ALIMENTAIRES, DE MALADIES ALLERGIQUES ET DE MALADIES INFLAMMATOIRES
  申请人：WESTERN NEW ENGLAND UNIV

  公开号：WO2019164874A1

  公开（公告）日：2019-08-29

  Disclosed are methods of treating, inhibiting, or preventing the development of, a food allergy in a patient by administering a therapeutically effective amount of a thiol isomerase inhibitor to a patient in need thereof. Also disclosed are methods for treatment of other allergic diseases and inflammatory diseases.