1-(2-Hexadec-9-enoxypropylsulfonyl)hexadecane

• 分子结构分类: 有机化合物 - 有机硫化合物 - 磺酰类
• 英文名称: 1-(2-Hexadec-9-enoxypropylsulfonyl)hexadecane
• 英文别名: 1-(2-hexadec-9-enoxypropylsulfonyl)hexadecane
• 化学式: C₃₅H₇₀O₃S
• 分子量: 571.0
• InChiKey: UCHWXJFSIXHWGP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.5
• 重原子数：
  39
• 可旋转键数：
  32
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  51.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• NOVEL SP-B&SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF
  申请人：University of Rochester

  公开号：EP2812018A2

  公开（公告）日：2014-12-17
• [EN] NOVEL SP-B & SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF<br/>[FR] NOUVEAUX PEPTIDES SP-B ET SP-C, TENSIOACTIFS PULMONAIRES SYNTHÉTIQUES, ET LEURS UTILISATIONS
  申请人：UNIV ROCHESTER

  公开号：WO2013120058A2

  公开（公告）日：2013-08-15

  The present invention relates to synthetic lung surfactant compositions that include a novel surface active peptide and a phospholipid, including phospholipase-resistant phospho-glycerol derivatives, phospholipase-resistant phospho-choline derivatives, naturally occurring phospholipids, or a combination thereof. Uses of the surfactant compositions of the present invention to treat endogenous surfactant dysfunctional or deficient lung tissue and to deliver therapeutic agents are also disclosed.