1,3-didecyl-2-methyl-2H-imidazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑啉类
• 英文名称: 1,3-didecyl-2-methyl-2H-imidazole
• 化学式: C₂₄H₄₈N₂
• 分子量: 364.7
• InChiKey: OVPKTTURAPIRFM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.1
• 重原子数：
  26
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] MANUFACTURE OF VINYL CHLORIDE BY HYDROCHLORINATION OF ACETYLENE IN THE PRESENCE OF A CATALYTIC SYSTEM CONSISTING OF AT LEAST ONE IONIC LIQUID<br/>[FR] FABRICATION DE CHLORURE DE VINYLE PAR HYDROCHLORATION D'ACÉTYLÈNE EN PRÉSENCE D'UN SYSTÈME CATALYTIQUE CONSTITUÉ D'AU MOINS UN LIQUIDE IONIQUE
  申请人：SOLVAY

  公开号：WO2012084642A1

  公开（公告）日：2012-06-28

  Catalytic system consisting essentially of at least one ionic liquid comprising at least one non-protonated cation and at least one anion selected from chloride and methanesulfonate and its use in the hydrochlorination reaction of acetylene with hydrogen chloride.

  催化系统基本上由至少一种离子液体组成，其中包括至少一种非质子化阳离子和至少一种氯化物和甲磺酸盐选择的阴离子，以及其在氢氯酸与乙炔的氢氯化反应中的应用。
• Process for the hydrohalogenation of an unsaturated hydrocarbon and for the manufacture of vinyl chloride by hydrochlorination of acetylene
  申请人：SOLVAY SA

  公开号：EP2617698A1

  公开（公告）日：2013-07-24

  Process for the hydrohalogenation of an unsaturated hydrocarbon using a catalyst comprising at least one ionic liquid (IL) and a metal, according to which said IL and metal are supported on a solid carrier, said process being a continuous industrial process wherein the overall unsaturated hydrocarbon conversion is of at least 60 % during at least 500 hours.

  使用至少一种离子液体（IL）和金属组成的催化剂，通过固体载体支持该IL和金属，进行不饱和烃的氢卤化反应的过程，该过程是连续的工业过程，其中整个不饱和烃的转化率在至少500小时内达到60％以上。
• [EN] METHOD FOR PREPARATION OF EFINACONAZOLE IN IONIC LIQUID MEDIUM<br/>[FR] PROCÉDÉ DE PRÉPARATION D'ÉFINACONAZOLE DANS UN MILIEU LIQUIDE IONIQUE<br/>[KO] 이온성 액체를 매개로 한 에피나코나졸의 신규 제조방법
  申请人：DAEBONG LS LTD

  公开号：WO2021060948A1

  公开（公告）日：2021-04-01

  본 발명은 이온성 액체를 매개로 한 에피나코나졸의 신규 제조방법에 관한 것으로서, 1-[[(2R,3S)-2-(2,4-디플루오르페닐)-3-메틸옥시란일]메틸]-1H-1,2,4-트리아졸, 및 4-메틸렌피페리딘 또는 이의 유기화학적으로 허용 가능한 염을 반응시키되, 상기 4-메틸렌피페리딘 또는 이의 유기화학적으로 허용 가능한 염을 염기 상에서 음이온화시키고, 이온성 액체 화합물 존재 하에서, 상기 1-[[(2R,3S)-2-(2,4-디플루오르페닐)-3-메틸옥시란일]메틸]-1H-1,2,4-트리아졸과 커플링 반응시키는 것을 특징으로 한다. 본 발명은 에피나코나졸 제조시 유기용매 대신에 이온성 액체를 사용함으로써, 기존의 방법보다 유연물질을 감소시켰으며, 반응시간을 단축하여 고순도 및 고수율로 최종 화합물인 에피나코나졸을 용이하게 수득할 수 있으며, 대량생산에 매우 적합하게 이용될 수 있다.

  本发明涉及一种以离子液体为媒介的新型环氧酮的制备方法，其中反应1-[[(2R,3S)-2-(2,4-二氟苯基)-3-甲氧基戊烷基]甲基]-1H-1,2,4-三唑和4-甲基亚硝基噻吩或其有机化学上可接受的盐，在碱的存在下将4-甲基亚硝基噻吩或其有机化学上可接受的盐负离子化，然后在离子液体存在下与1-[[(2R,3S)-2-(2,4-二氟苯基)-3-甲氧基戊烷基]甲基]-1H-1,2,4-三唑进行偶联反应。本发明通过使用离子液体代替有机溶剂，在环氧酮制备过程中减少了弹性物质的量，并缩短了反应时间，可以轻松获得高纯度和高收率的最终化合物环氧酮，非常适合大规模生产。
• PROTECTANT FOR ELECTRON MICROSCOPE OBSERVATION OF HYDRATED BIOLOGICAL SAMPLE, KIT FOR ELECTRON MICROSCOPE OBSERVATION, METHOD FOR OBSERVATION, DIAGNOSIS, EVALUATION, OR QUANTIFICATION BY ELECTRON MICROSCOPE, AND SAMPLE STAGE
  申请人：Japan Science and Technology Agency

  公开号：EP3101407A1

  公开（公告）日：2016-12-07

  Provided are a protective agent for electron microscopic observation in a vacuum which can protect a biological sample in a water-containing state, such as a mammal, a plant tissue or a cultured cell, and a single cell in the living state without deforming it even in a vacuum, a kit using the same, methods for observation, diagnosis, evaluation, and quantification of a sample by an electron microscope, and a sample stage to be used for the observation. The protective agent for electron microscopic observation of the present invention contains a survival environment imparting component, a saccharide, and an electrolyte.

  本发明提供了一种用于在真空中进行电子显微镜观察的保护剂，它可以保护含水状态下的生物样品，如哺乳动物、植物组织或培养细胞，以及活体状态下的单细胞，即使在真空中也不会使其变形；还提供了一种使用该保护剂的试剂盒、一种用电子显微镜对样品进行观察、诊断、评估和定量的方法，以及一种用于观察的样品台。本发明的用于电子显微镜观察的保护剂含有生存环境赋予成分、糖类和电解质。
• Protective agent for electron microscopic observation of biological sample in water-containing state, kit for electron microscopic observation, methods for observation, diagnosis, evaluation, and quantification by electron microscope, and sample stage
  申请人：JAPAN SCIENCE AND TECHNOLOGY AGENCY

  公开号：US10128078B2

  公开（公告）日：2018-11-13

  Provided are a protective agent for electron microscopic observation in a vacuum which can protect a biological sample in a water-containing state, such as a mammal, a plant tissue or a cultured cell, and a single cell in the living state without deforming it even in a vacuum, a kit using the same, methods for observation, diagnosis, evaluation, and quantification of a sample by an electron microscope, and a sample stage to be used for the observation. The protective agent for electron microscopic observation of the present invention contains a a component to impart the survival environment, a saccharide, and an electrolyte.

  本发明提供了一种用于在真空中进行电子显微镜观察的保护剂，该保护剂可以保护含水状态下的生物样品，如哺乳动物、植物组织或培养细胞，以及活体状态下的单细胞，即使在真空中也不会使其变形；还提供了使用该保护剂的试剂盒、通过电子显微镜对样品进行观察、诊断、评估和定量的方法，以及用于观察的样品台。本发明用于电子显微镜观察的保护剂含有一种赋予生存环境的成分、一种糖类和一种电解质。