Trimethyl(3-methylsulfonylsulfanylpropyl)azanium

• 分子结构分类: 有机化合物 - 有机硫化合物 - 磺酰类
• 英文名称: Trimethyl(3-methylsulfonylsulfanylpropyl)azanium
• 化学式: C7H18NO2S2+
• 分子量: 212.4
• InChiKey: FTOBGHBOYZUIFI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  67.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• METHOD FOR PRODUCING REAGENT FOR ANTIBODY DETECTION AND USE THEREOF
  申请人：Medinet Co., Ltd.

  公开号：EP2833143A1

  公开（公告）日：2015-02-04

  The present invention provides the following: a method for efficiently producing a reagent for detecting an antibody that specifically binds with an insoluble antigen protein present in a liquid sample; a reagent for antibody detection produced by the production method; and a use of the antibody. In a step for solubilizing an antigen protein, it is possible to efficiently solubilize and recover the antigen protein by using a cationizing agent; therefore, when compared to conventional methods, it is possible to efficiently produce a reagent for detecting an antibody that has bound to multiple antigen protein molecules in a carrier.

  本发明提供了以下内容：一种高效生产用于检测抗体的试剂的方法，该试剂可与存在于液体样品中的不溶性抗原蛋白特异性结合；一种由该生产方法生产的用于检测抗体的试剂；以及该抗体的用途。在溶解抗原蛋白的步骤中，通过使用阳离子化剂，可以高效地溶解和回收抗原蛋白；因此，与传统方法相比，可以高效地生产用于检测与载体中多个抗原蛋白分子结合的抗体的试剂。
• Method for producing reagent for antibody detection and use thereof
  申请人：Futami Junichiro

  公开号：US10822384B2

  公开（公告）日：2020-11-03

  The present invention provides the following: a method for efficiently producing a reagent for detecting an antibody that specifically binds with an insoluble antigen protein present in a liquid sample; a reagent for antibody detection produced by the production method; and a use of the antibody. In a step for solubilizing an antigen protein, it is possible to efficiently solubilize and recover the antigen protein by using a cationizing agent; therefore, when compared to conventional methods, it is possible to efficiently produce a reagent for detecting an antibody that has bound to multiple antigen protein molecules in a carrier.

  本发明提供了以下内容：一种高效生产用于检测抗体的试剂的方法，该试剂可与存在于液体样品中的不溶性抗原蛋白特异性结合；一种由该生产方法生产的用于检测抗体的试剂；以及该抗体的用途。在溶解抗原蛋白的步骤中，通过使用阳离子化剂，可以高效地溶解和回收抗原蛋白；因此，与传统方法相比，可以高效地生产用于检测与载体中多个抗原蛋白分子结合的抗体的试剂。
• METHOD FOR DETECTING AN ANTIGEN-SPECIFIC ANTIBODY AND REAGENT FOR USE THEREIN
  申请人：Junichiro FUTAMI

  公开号：US20210032302A1

  公开（公告）日：2021-02-04

  A method for detecting an antigen-specific antibody detection reagent, which includes a cationized, denatured antigenic protein immobilized on a solid-phase surface of a carrier material, is provided. The cationized, denatured antigenic protein has cationized SH groups formed from reaction with a cationizing agent. The detection reagent is capable of specifically binding to an antigen-specific antibody which binds to an epitope of the antigenic protein. The method includes contacting a sample containing the antigen-specific antibody with the detection reagent to bind the antigen-specific antibody with the detection reagent. A labeled secondary antibody is then added to allow the labeled secondary antibody to bind to the antigen-specific antibody; and the detection reagent bound with the antigen-specific antibody is detected.