2-Azabicyclo[2.2.1]heptan-5-ol hydrochloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 2-Azabicyclo[2.2.1]heptan-5-ol hydrochloride
• 英文别名: 2-azabicyclo[2.2.1]heptan-5-ol;hydrochloride
• 化学式: C6H12ClNO
• 分子量: 149.62
• InChiKey: LUTVSQCTGHUTOO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.15
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  32.3
• 氢给体数：
  3
• 氢受体数：
  2

文献信息

• Heterocyclic compounds as immunomodulators
  申请人：Incyte Corporation

  公开号：US10308644B2

  公开（公告）日：2019-06-04

  Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.

  本发明公开了式（I）化合物、将这些化合物用作免疫调节剂的方法以及包含这些化合物的药物组合物。这些化合物可用于治疗、预防或改善癌症或感染等疾病或紊乱。
• BENZOOXAZOLE DERIVATIVES AS IMMUNOMODULATORS
  申请人：Incyte Corporation

  公开号：EP3558985A1

  公开（公告）日：2019-10-30
• HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS
  申请人：Incyte Corporation

  公开号：US20180179197A1

  公开（公告）日：2018-06-28

  Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.
• [EN] BENZOOXAZOLE DERIVATIVES AS IMMUNOMODULATORS<br/>[FR] DÉRIVÉS DE BENZOOXAZOLE EN TANT QU'MMUNOMODULATEURS
  申请人：INCYTE CORP

  公开号：WO2018119266A1

  公开（公告）日：2018-06-28

  Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.