1-Phenyl-4,4-dimethyl-piperidin | 92195-54-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-Phenyl-4,4-dimethyl-piperidin
• 英文别名: 4,4-dimethyl-1-phenyl-piperidine；4,4-Dimethyl-1-phenyl-piperidin；4,4-Dimethyl-1-phenylpiperidine
• CAS: 92195-54-5
• 化学式: C₁₃H₁₉N
• 分子量: 189.301
• InChiKey: RUPQVIUCCLWWSR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4,4-dimethyl-1-phenyl-3,4-dihydropyridin-2(1H)-one 、 Lithium aluminium hydride 、 芒硝 、 Sodium sulfate-III 、 、 1-Phenyl-4,4-dimethyl-piperidin 在 乙醚 作用下， 以 乙醚 为溶剂， 反应 1.67h， 生成 4,4-dimethyl-1-phenyl-1,2,3,4-tetrahydropyridine
  参考文献：
  名称：

  UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof

  摘要：

  提供了一系列新颖的化合物，已经证明具有有用的紫外线吸收性能。这些化合物将在各种应用中发挥作用，例如作为防晒霜配方、涂料、塑料、织物、玻璃和紫外线防护涂层的活性成分。

  公开号：

  US20160244409A1
• 作为产物：
  描述：

  1,5-二溴-3,3-二甲基戊烷 、 苯胺 在 甲基环己烷 作用下， 生成 1-Phenyl-4,4-dimethyl-piperidin
  参考文献：
  名称：

  Condensation of Saturated Halides with Unsaturated Compounds. VIII. Condensation of Dihaloalkanes with Ethylene and Chloroethylenes¹

  摘要：

  DOI：

  10.1021/ja01131a049

文献信息

• [EN] UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF<br/>[FR] COMPOSÉS ABSORBANT LES UV, COMPOSITIONS LES CONTENANT ET LEURS UTILISATIONS
  申请人：CORAL SUNSCREEN PTY LTD

  公开号：WO2015006803A1

  公开（公告）日：2015-01-22

  There is provided a range of novel compounds which have been demonstrated to have useful UV absorbing properties. These compounds will find use in a range of applications such as active components in sunscreen formulations, paints, plastics, fabrics, glass and UV protective coatings.

  提供了一系列新化合物，已经证明具有有用的吸收紫外线性能。这些化合物将在各种应用中发挥作用，如防晒霜配方中的活性成分、油漆、塑料、织物、玻璃和紫外线防护涂料。
• ORGANIC ELECTROLUMINESCENCE DEVICE, NOVEL PLATINUM COMPLEX COMPOUND AND NOVEL COMPOUND CAPABLE OF BEING A LIGAND THEREOF
  申请人：Murakami Takeshi

  公开号：US20090261721A1

  公开（公告）日：2009-10-22

  An organic electroluminescence device, includes: a pair of electrodes; and at least one organic layer including a light emitting layer, the light emitting layer being provided between the pair of electrodes, wherein at least one layer of the at least one organic layer contains a compound represented by formula (1) as defined in the specification.

  一种有机电致发光装置，包括：一对电极；以及至少一层有机层，包括发光层，所述发光层位于电极对之间，其中，所述至少一层有机层中至少含有一种由式（1）所表示的化合物，该式在说明书中有定义。
• POLYMERIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT COMPRISING THE SAME
  申请人：Idemitsu Kosan Co., Ltd.

  公开号：EP2213693A1

  公开（公告）日：2010-08-04

  A polymer comprising the repeating units derived from an aromatic compound having a specific structure and a repeating unit derived from the compound represented by formula (1): wherein Ar1 to Ar4 are each independently a substituted or unsubstituted aryl group having 6 to 40 ring-forming carbon atoms, a substituted or unsubstituted heterocyclic group having 3 to 40 ring-forming atoms, a substituted or unsubstituted alkyl group having 1 to 50 carbon atoms; X is a substituted or unsubstituted aryl group having 6 to 40 ring-forming carbon atoms, a substituted or unsubstituted heterocyclic group having 3 to 40 ring-forming atoms, or a substituted or unsubstituted di- to tetravalent styrene-derived group; and s is an integer of 0 to 3. The polymer is useful as a light emission material and realizes a polymer electroluminescence device excellent in device characteristics such as lifetime and emission efficiency.

  一种聚合物，包含由具有特定结构的芳香族化合物衍生的重复单元和由式（1）代表的化合物衍生的重复单元： 其中 Ar1 至 Ar4 各自独立地为具有 6 至 40 个成环碳原子的取代或未取代芳基、具有 3 至 40 个成环原子的取代或未取代杂环基、具有 1 至 50 个碳原子的取代或未取代烷基；X 是具有 6 至 40 个成环碳原子的取代或未取代的芳基、具有 3 至 40 个成环原子的取代或未取代的杂环基团或取代或未取代的二价至四价苯乙烯衍生基团；以及 s 是 0 至 3 的整数。这种聚合物可用作光发射材料，并实现一种在寿命和发射效率等器件特性方面性能优异的聚合物电致发光器件。
• POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME
  申请人：Idemitsu Kosan Co., Ltd.

  公开号：EP2223949A1

  公开（公告）日：2010-09-01

  A polymer comprising a repeating unit derived from a compound represented by formula (1): wherein X1 to X10 are as defined in the specification and a repeating unit derived from an aromatic compound having a specific structure. The polymer is useful as a light emission material and realizes a polymer electroluminescence device excellent in device characteristics such as lifetime and emission efficiency.

  一种聚合物，包含由式（1）代表的化合物衍生的重复单元： 其中 X1 至 X10 如说明书中所定义，以及一个衍生自具有特定结构的芳香族化合物的重复单元。该聚合物可用作光发射材料，并实现一种在寿命和发射效率等器件特性方面性能优异的聚合物电致发光器件。
• BMP-SIGNAL-INHIBITING COMPOUND
  申请人：Riken

  公开号：EP3564232A1

  公开（公告）日：2019-11-06

  The present invention relates to novel and excellent small-molecule-compounds that specifically antagonize BMP signal pathways, and these compounds can be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus can be used to treat diseases or pathological symptoms related to BMP signal pathway including inflammation, cardiovascular diseases, hematopoietic diseases, cancer, osteodystrophia, or the like, particularly, fibrodysplasia ossificans progressiva, and the present invention relates to provision of a pharmaceutical and pharmacological agent used for specifically antagonizing the BMP signal pathways and acting on the BMP signal pathways in the prevention and treatment or experimental application since the compounds can be beneficial for regulating cell differentiation and/or cell proliferation.

  本发明涉及特异性拮抗BMP信号通路的新型优良小分子化合物，这些化合物可用于调节细胞生长、分化、增殖和凋亡，从而可用于治疗与BMP信号通路相关的疾病或病理症状，包括炎症、心血管疾病、造血疾病、癌症、骨营养不良症、本发明涉及提供一种用于特异性拮抗 BMP 信号通路并作用于 BMP 信号通路的药物和药理制剂，以预防和治疗或实验应用，因为该化合物可有益于调节细胞分化和/或细胞增殖。