2-(1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-yl)acetic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 2-(1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-yl)acetic acid
• 化学式: C₁₁H₂₁NO₃
• 分子量: 215.29
• InChiKey: UZWBDSQDACNUFX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  60.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Inhibition of pulp and paper yellowing using nitroxides, hydroxylamines and other coadditives
  申请人：——

  公开号：US20020124980A1

  公开（公告）日：2002-09-12

  Pulps or papers, especially chemimechanical or thermomechanical pulps or papers, which still contain lignin, have enhanced resistance to yellowing when they contain an effective stabilizing amount of a hindered amine compound which preferably is a nitroxide, a hydroxylamine or an ammonium salt thereof. This performance is often further enhanced by the presence of one or more coadditives selected from the group consisting of the UV absorbers, the polymeric inhibitors, the nitrones, the fluorescent whitening agents, metal chelating agents, sulfur containing stabilizers, metal salts and diene compounds. Combinations of nitroxides, hydroxylamines or their salts, benzotriazole or benzophenone UV absorbers and a metal chelating agent are particularly effective. Selected derivatives of 1-oxyl-2,2,6,6-tetramethyl-piperidin-4-ol and selected hydroxylamine salts are novel compounds and are surprisingly effective for this purpose.

  含有木质素的纸浆或纸张，特别是化学机械或热机械纸浆或纸张，如果它们含有有效的阻化胺化合物（最好是亚硝基自由基，羟胺或其铵盐），则具有增强的抗黄变性能。当与来自紫外线吸收剂、聚合抑制剂、亚硝基醇、荧光增白剂、金属螯合剂、含硫稳定剂、金属盐和二烯化合物等组成的一种或多种协同添加剂一起使用时，通常可以进一步提高其性能。亚硝基自由基、羟胺或其盐、苯并三唑或苯并酚类紫外线吸收剂和金属螯合剂的组合尤其有效。选择的1-氧基-2,2,6,6-四甲基哌啶-4-醇和选择的羟胺盐衍生物是新的化合物，出乎意料地有效。
• Stabilizers for the Stabilization of Unsaturated Hydrocarbon-Based Precursor
  申请人：Mayorga Steven Gerard

  公开号：US20110218371A1

  公开（公告）日：2011-09-08

  A stabilized composition consists essentially of unsaturated hydrocarbon-based materials, and a stabilizer selected from the group consisting of a hydroxybenzophenone and a nitroxyl radical based stabilizer. A method for stabilizing unsaturated hydrocarbon-based precursor material against the polymerization comprises providing a stabilizer selected from the group consisting of a hydroxybenzophenone and a nitroxyl radical based stabilizer.

  一种稳定组合物主要由不饱和碳氢化合物材料和从羟基苯酮和基于亚硝基自由基的稳定剂中选择的稳定剂组成。一种稳定不饱和碳氢化合物前驱材料的方法包括提供从羟基苯酮和基于亚硝基自由基的稳定剂中选择的稳定剂。
• Stabiliserte wässrige Dispersionen von Polymeren mit ethylenisch ungesättigten Gruppen
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：EP0801092A2

  公开（公告）日：1997-10-15

  Wäßrige Dispersionen von Verbindungen mit copolymerisierbaren, ethylenisch ungesättigten Gruppen, enthaltend einen Stabilisator, der mindestens eine in 2,2,6,6-Stellung durch eine C1-C6-Kohlenwasserstoffgruppe tetrasubstituierte Piperidin-N-oxyl-Gruppe enthält.

  具有可共聚的乙烯不饱和基团的化合物的水分散体，含有一种稳定剂，该稳定剂至少含有一个在 2,2,6,6 位上由 C1-C6 碳氢基团四取代的哌啶-N-氧基。
• Verfahren zum Verdichten ethylenisch ungesättigter Monomerer
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：EP0811590A1

  公开（公告）日：1997-12-10

  Verfahren zum Verdichten von ethylenisch ungesättigten Monomeren auf einem Druck zwischen 200 und 5000 bar in Abwesenheit eines Polymerisationsinitiators, dadurch gekennzeichnet, daß die Verdichtung in Gegenwart eines sterisch gehinderten Aminderivats vorgenommen wird.

  在没有聚合引发剂的情况下，将乙烯不饱和单体压缩至 200 至 5000 巴压力的工艺，其特征在于压缩是在有立体受阻胺衍生物存在的情况下进行的。
• NOVEL NITROXYL COMPOUNDS AND DRUGS AND REAGENTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT
  申请人：DAIICHI RADIOISOTOPE LABORATORIES, LTD.

  公开号：EP0995740A1

  公开（公告）日：2000-04-26

  Nitroxyl compounds represented by general formula (I) which are usable in acquiring information about active oxygen or in vivo free radicals as biological images such as magnetic resonance images or magnetoencephalograms, wherein A represents hydrogen or -L-(CH2)n-OCOR (wherein L represents -COO- or -alkylene-COO-; and R represents C1-4 alkyl); R1, R2, R3, and R4 represent each C1-4 alkyl; and n is a number of from 1 to 4. Drugs and reagents containing the above compounds are usable in preventing, treating or diagnosing ischemic diseases, digestive diseases, cancer, cranial nervous diseases accompanied by nerve degeneration, inflammation, cataracts, or drug-induced organopathy.

  通式(I)代表的硝氧化合物，可用于获取活性氧或体内自由基的信息，作为生物图像，如磁共振图像或磁共振脑电图，其中 A 代表氢或-L-(CH2)n-OCOR（其中 L 代表-COO-或-亚烷基-COO-；R 代表 C1-4 烷基）；R1、R2、R3 和 R4 分别代表 C1-4 烷基；n 是 1 到 4 的数字。含有上述化合物的药物和试剂可用于预防、治疗或诊断缺血性疾病、消化系统疾病、癌症、伴有神经变性的颅神经疾病、炎症、白内障或药物引起的器官病变。